|Related Categories||Adrenocorticotrophic Hormone (ACTH), Adrenocorticotropic Hormones (ACTH), Cell Biology, Cell Signaling and Neuroscience, Cytokines, Growth Factors and Hormones,|
|composition||Peptide content, ≥60%|
|Gene Information||human ... POMC(5443)|
Activates G proteins.
The portion of the ACTH sequence that is conserved across species; has ~75% of the potency of ACTH on a molar basis.
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powder, 80-95 IU/mg (USP Corticotropin Ascorbic Acid Assay)
Use of PET/CT with cosyntropin stimulation to identify and localize adrenal rest tissue following adrenalectomy in a woman with congenital adrenal hyperplasia. Crocker MK, Barak S, Millo CM, et al. J. Clin. Endocrinol. Metab. 97(11), E2084-9, (2012)
Measurements of serum DHEA and DHEA sulphate levels improve the accuracy of the low-dose cosyntropin test in the diagnosis of central adrenal insufficiency. Sayyed Kassem L, El Sibai K, Chaiban J, et al. J. Clin. Endocrinol. Metab. 97(10), 3655-62, (2012)
Comparison of low and high dose cosyntropin stimulation tests in the diagnosis of adrenal insufficiency in septic shock patients. Moraes RB, Friedman G, Tonietto T, et al. Horm. Metab. Res. 44(4), 296-301, (2012)
Free and total plasma cortisol measured by immunoassay and mass spectrometry following ACTH₁₋₂₄ stimulation in the assessment of pituitary patients. Burt MG, Mangelsdorf BL, Rogers A, et al. J. Clin. Endocrinol. Metab. 98(5), 1883-90, (2013)
High prevalence of adrenal insufficiency in patients with sickle cell disease: results from a community hospital in the U.S. Makino J, Ndzengue A, Adekolujo S, et al. Exp. Clin. Endocrinol. Diabetes 121(1), 32-6, (2013)
Evaluation of serum concentrations of cortisol and sex hormones of adrenal gland origin after stimulation with two synthetic ACTH preparations in clinically normal dogs. Ginel PJ, Sileo MT, Blanco B, et al. Am. J. Vet. Res. 73(2), 237-41, (2012)
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