• USA Home
  • A0409 - Anti-α1-Antitrypsin antibody produced in rabbit

EMAIL THIS PAGE TO A FRIEND
A0409 Sigma

Anti-α1-Antitrypsin antibody produced in rabbit

IgG fraction of antiserum

Synonym: anti-A1AT

Purchase

Properties

Related Categories AM-AN, Alphabetical Index, Antibodies, Antibodies to Human Plasma Proteins, Primary Antibodies,
species reactivity   human
application(s)   immunoelectrophoresis: suitable
  indirect ELISA: 1:30,000-1:60,000
clone   polyclonal
antibody form   IgG fraction of antiserum
mol wt   antigen mol wt ~50 kDa
storage temp.   2-8°C
Gene Information   human ... SERPINA1(5265)
biological source   rabbit
packaging   vial of 2 mL lyophilized antiserum
conjugate   unconjugated

Description

Immunogen

Purified human α-1-antitrypsin

General description

α-1-antitrypsin belongs to the serpin family and is a strong serine protease inhibitor. Its pivotal role is to protect lower respiratory tract against proteolytic destruction by human leukocyte elastase. Mutation in AAT gene will reduce the serum concentration of α-1-antitrypsin and hence increase the risk of emphysema. Anti-α1-antitrypsin antibody (diluted 1:9000) can be used as a capture antibody for determination of transgene expressions levels. It can also be used in immunoelectrophoresis. Rabbit anti-α1-antitrypsin antibody reacts specifically with α1-antitrypsin of human.

Physical form

Lyophilized from 0.01 M phosphate buffered saline, pH 7.2.

Application

Anti-α1-antitrypsin antibody (diluted 1: 1000) can be used in ELISA. It can also be used for probing immunoblots to identify A1AT. Additionally, it can be used in Ouchterlony double diffusion.

Applications in which this antibody has been used successfully, and the associated peer-reviewed papers, are given below.
Western Blotting (1 paper)

Rabbit anti-α1-antitrypsin antibody can also be used in immunoelectrophoretic techniques.

Price and Availability


Antibody Explorer

Explore with Confidence
Safety & Documentation

Safety Information

RIDADR  NONH for all modes of transport
WGK Germany  3
Protocols & Articles

Related Content

Antibody Explorer | Buy Primary & Secondary Antibodies

Monoclonal and polyclonal primary antibodies are focused on cell biology, neurobiology and molecular biology. Secondary antibodies targeting multiple host’s IgG are conjugated to alkaline phosphatase...
Keywords: Amplification, Buffers, Cell biology, Enzyme-linked immunosorbent assay, Immunofluorescence, Immunohistochemistry, Inflammation, Molecular biology, Phosphorylations, Purification, Western blot

Peer-Reviewed Papers
15

References

Related Products

Technical Service:

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Bulk Ordering & Pricing:

Need larger quantities for your development, manufacturing or research applications?