• USA Home
  • A0466 - N-Acetyl-Asp-Glu-Val-Asp-7-amido-4-trifluoromethylcoumarin

EMAIL THIS PAGE TO A FRIEND
A0466 Sigma

N-Acetyl-Asp-Glu-Val-Asp-7-amido-4-trifluoromethylcoumarin

≥90% (HPLC), powder

Synonym: Ac-DEVD-AFC

Purchase

Description

Amino Acid Sequence

NAc-Asp-Glu-Val-Asp-AFC

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

Biochem/physiol Actions

A fluorogenic substrate for caspase 3, a protease that is rapidly activated when cells are exposed to apoptotic conditions and that cleaves poly(ADP-ribose) polymerase. The 7-amido-4-trifluoromethylcoumarin derivative has better membrane permeability than the 7-amido-4-methylcoumarin derivative (A1086).

Price and Availability


Flow Cytometry Instruments

Amicon Ultra Centrifugal Filters
Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
3
Protocols & Articles
Peer-Reviewed Papers
15

References

Set your institution to view full text papers.
Related Products

Technical Service:

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Bulk Ordering & Pricing:

Need larger quantities for your development, manufacturing or research applications?