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A0682 Sigma

Alginic acid sodium salt from brown algae

BioReagent, plant cell culture tested, low viscosity, powder

Synonym: Algin, Sodium alginate

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Properties

Related Categories Biochemicals and Reagents, Carbohydrate, Carbohydrates, Cell Biology, Gelling Agents,
product line   BioReagent
form   powder
viscosity   4-12 cP, 1 % in H2O(25 °C)(lit.)
suitability   plant cell culture tested
Featured Industry   Agriculture

Description

Other Notes

A straight-chain, hydrophilic, colloidal, polyuronic acid composed of glucuronic and mannuronic acid residues.

Application

Alginic acid, alginate, is an anionic polysaccharide distributed widely in the cell walls of brown algae. Alginate is biocompatible and gels in the presence of divalent cations such as calcium making it useful for cell encapsulation and immobilization. Immobilized cells have use in bioproduction and bioremediation processes.

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WGK Germany 
1

Protocols & Articles

Peer-Reviewed Papers

References

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Dynamic tissue engineering scaffolds with stimuli-responsive macroporosity formation. Han LH, Lai JH, Yu S, et al. Biomaterials 34(17), 4251-8, (2013)

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Co-encapsulation of anti-BMP2 monoclonal antibody and mesenchymal stem cells in alginate microspheres for bone tissue engineering. Moshaverinia A, Ansari S, Chen C, et al. Biomaterials 34(28), 6572-9, (2013)

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Preparation of alginate beads containing a prodrug of diethylenetriaminepentaacetic acid. Yang YT, Di Pasqua AJ, He W, et al. Carbohydr. Polym. 92(2), 1915-20, (2013)

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Droplet-based microfluidic system to form and separate multicellular spheroids using magnetic nanoparticles. Yoon S, Kim JA, Lee SH, et al. Lab Chip 13(8), 1522-8, (2013)

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Dynamics of biofilm formation under different nutrient levels and the effect on biofouling of a reverse osmosis membrane system. Chen X, Suwarno SR, Chong TH, et al. Biofouling 29(3), 319-30, (2013)

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Should we isolate human preantral follicles before or after cryopreservation of ovarian tissue? Vanacker J, Luyckx V, Amorim C, et al. Fertil. Steril. 99(5), 1363-1368.e2, (2013)

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Alginate: an alternative to agar in plant protoplast culture. Adaoha Mbanaso, E.N. and Roscoe, D.H. Plant Sci. Lett. 25, 61-66, (1982)

Regeneration, cultivation and differentiation of plant protoplasts immobilized in Ca-alginate beads. J. Draget, K.I., et al. Plant Physiol. 132, 552-556, (1988)

Nurse culture of low numbers of Medicago and Nicotiana protoplasts using calcium alginate beads. Larkin, P.J., et al. Plant Sci. 58, 203-210, (1988)

Ultrapure alginate anti-adhesion gel does not impair colon anastomotic strength. Chaturvedi AA, Lomme RM, Hendriks T, et al. J. Surg. Res. 192(2), 432-9, (2014)

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High removal of chemical and biochemical oxygen demand from tequila vinasses by using physicochemical and biological methods. Retes-Pruneda JL, Davila-Vazquez G, Medina-Ramírez I, et al. Environ. Technol. 35(13-16), 1773-84, (2014)

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Extracellular matrix stiffness and composition jointly regulate the induction of malignant phenotypes in mammary epithelium. Chaudhuri O, Koshy ST, Branco da Cunha C, et al. Nat. Mater. 13(10), 970-8, (2014)

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The use of alginate dressing on grafted donor sites in burns. Salibi A and Farroha A Ann. R. Coll. Surg. Engl. 96(3), 239-40, (2014)

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Magnetic alginate-layered double hydroxide composites for phosphate removal. Lee CG and Kim SB Environ. Technol. 34(17-20), 2749-56, (2013)

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Functional characterization of polysaccharide utilization loci in the marine Bacteroidetes 'Gramella forsetii' KT0803. Kabisch A, Otto A, König S, et al. ISME J. 8(7), 1492-502, (2014)

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Alginate immobilization of Escherichia coli MTCC 1652 whole cells for bioconversion of glycyrrhizinic acid and into 18-beta glycyrrhetinic acid. Ahmad M and Panda BP Pak. J. Biol. Sci. 16(24), 2046-9, (2013)

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Synthesis of carboxymethyl chitosan and coating on wound dressing gauze for wound healing. Venkatrajah B, Malathy VV, Elayarajah B, et al. Pak. J. Biol. Sci. 16(22), 1438-48, (2013)

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[Preparation of cinnamomi cortex oil microspheres based on porous silicon dioxide and its property characterizations]. Zhu CX, Jiang YR, Zhang ZH, et al. Zhongguo Zhong Yao Za Zhi 38(20), 3479-83, (2013)

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[Treatment of infected diabetic foot ulcers clinical effectiveness of a dressing of alginate and hydrocolloid, with silver fiber. Analysis of results of a series of cases]. Lázaro-Martínez JL, Cecilia-Matilla A, Aragón-Sánchez J, et al. Rev. Enferm. 36(11), 29-34, (2013)

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Strategies based on silica monoliths for removing pollutants from wastewater effluents: a review. Rodrigues D, Rocha-Santos TA, Freitas AC, et al. Sci. Total Environ. 461-462, 126-38, (2013)

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Applications of nanoparticles for treating cutaneous infection. Westendorf AM J. Invest. Dermatol. 133(5), 1133-5, (2013)

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An in vitro comparison of working length determination by two motor-driven electronic apex locators. Koçak MM, Koçak S, Helvaciođlu Kivanç B, et al. Minerva Stomatol. 62(3), 57-61, (2013)

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Microencapsulation of pancreatic islets for use in a bioartificial pancreas. Opara EC, McQuilling JP, and Farney AC Methods Mol. Biol. 1001, 261-6, (2013)

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Preparation and evaluation of sustained release calcium alginate beads and matrix tablets of acetazolamide. Barzegar-Jalali M, Hanaee J, Omidi Y, et al. Drug Res. (Stuttg.) 63(2), 60-4, (2013)

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Alginate-based strategies for therapeutic vascularization. Gandhi JK, Opara EC, and Brey EM Ther. Deliv. 4(3), 327-41, (2013)

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Preparation, characterization and adsorption properties of a novel 3-aminopropyltriethoxysilane functionalized sodium alginate porous membrane adsorbent for Cr(III) ions. Chen JH, Xing HT, Guo HX, et al. J. Hazard. Mater. 248-249, 285-94, (2013)

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Novel microparticulate systems for the vaginal delivery of nystatin: development and characterization. Martín-Villena MJ, Fernández-Campos F, Calpena-Campmany AC, et al. Carbohydr. Polym. 94(1), 1-11, (2013)

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Novel pharmaceutical approaches to reflux disease. Dutta U and Armstrong D Gastroenterol. Clin. North Am. 42(1), 93-117, (2013)

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Lactoferricin enhances BMP7-stimulated anabolic pathways in intervertebral disc cells. Ellman MB, Kim J, An HS, et al. Gene 524(2), 282-91, (2013)

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Hydrogels that mimic developmentally relevant matrix and N-cadherin interactions enhance MSC chondrogenesis. Bian L, Guvendiren M, Mauck RL, et al. Proc. Natl. Acad. Sci. U. S. A. 110(25), 10117-22, (2013)

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Facile fabrication of uniform size-controlled microparticles and potentiality for tandem drug delivery system of micro/nanoparticles. Iwanaga S, Saito N, Sanae H, et al. Colloids Surf. B Biointerfaces 109, 301-6, (2013)

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Combined UV-protecting and reactive printing of Cellulosic/wool blends. Ibrahim NA, El-Zairy EM, Abdalla WA, et al. Carbohydr. Polym. 92(2), 1386-94, (2013)

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Modeling studies: Adsorption of aniline blue by using Prosopis Juliflora carbon/Ca/alginate polymer composite beads. Kumar M and Tamilarasan R Carbohydr. Polym. 92(2), 2171-80, (2013)

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Biodegradable multilayer barrier films based on alginate/polyethyleneimine and biaxially oriented poly(lactic acid). Gu CH, Wang JJ, Yu Y, et al. Carbohydr. Polym. 92(2), 1579-85, (2013)

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A novel pulsed drug-delivery system: polyelectrolyte layer-by-layer coating of chitosan-alginate microgels. Zhou G, Lu Y, Zhang H, et al. Int. J. Nanomedicine 8, 877-87, (2013)

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Prevention of postsurgical adhesions using an ultrapure alginate-based gel. Chaturvedi AA, Lomme RM, Hendriks T, et al. Br. J. Surg. 100(7), 904-10, (2013)

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Diffusion of ions in a calcium alginate hydrogel-structure is the primary factor controlling diffusion. Golmohamadi M and Wilkinson KJ Carbohydr. Polym. 94(1), 82-7, (2013)

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pH-sensitive microparticles for oral drug delivery based on alginate/oligochitosan/Eudragit(®) L100-55 "sandwich" polyelectrolyte complex. Calija B, Cekić N, Savić S, et al. Colloids Surf. B Biointerfaces 110, 395-402, (2013)

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Alginate-based microcapsules with a molecule recognition linker and photosensitizer for the combined cancer treatment. Du C, Zhao J, Fei J, et al. Chem. Asian J. 8(4), 736-42, (2013)

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Genes required for and effects of alginate overproduction induced by growth of Pseudomonas aeruginosa on Pseudomonas isolation agar supplemented with ammonium metavanadate. Damron FH, Barbier M, McKenney ES, et al. J. Bacteriol. 195(18), 4020-36, (2013)

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Cryopreservation of alginate encapsulated mesenchymal stromal cells. Pravdyuk AI, Petrenko YA, Fuller BJ, et al. Cryobiology 66(3), 215-22, (2013)

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Systematic study of alginate-based microcapsules by micropipette aspiration and confocal fluorescence microscopy. Kleinberger RM, Burke NA, Dalnoki-Veress K, et al. Mater. Sci. Eng. C. Mater. Biol. Appl. 33(7), 4295-304, (2013)

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Digging into the extracellular matrix of a complex microbial community using a combined metagenomic and metaproteomic approach. Albertsen M, Stensballe A, Nielsen KL, et al. Water Sci. Technol. 67(7), 1650-6, (2013)

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Mapping global effects of the anti-sigma factor MucA in Pseudomonas fluorescens SBW25 through genome-scale metabolic modeling. Borgos SE, Bordel S, Sletta H, et al. BMC Syst. Biol. 7, 19, (2013)

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Cellular capsules as a tool for multicellular spheroid production and for investigating the mechanics of tumor progression in vitro. Alessandri K, Sarangi BR, Gurchenkov VV, et al. Proc. Natl. Acad. Sci. U. S. A. 110(37), 14843-8, (2013)

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Effect of alginate/nano-Ag coating on microbial and physicochemical characteristics of shiitake mushroom (Lentinus edodes) during cold storage. Jiang T, Feng L, and Wang Y Food Chem. 141(2), 954-60, (2013)

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Osteoblast differentiation and phenotype expressions on chitosan-coated Ti-6Al-4V. Lin HY and Chen JH Carbohydr. Polym. 97(2), 618-26, (2013)

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Production optimization of invertase by Lactobacillus brevis Mm-6 and its immobilization on alginate beads. Awad GE, Amer H, El-Gammal EW, et al. Carbohydr. Polym. 93(2), 740-6, (2013)

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Preparation and characterization of sodium alginate modified with collagen peptides. Fan L, Cao M, Gao S, et al. Carbohydr. Polym. 93(2), 380-5, (2013)

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Poly(vinyl alcohol)/sodium alginate/layered silicate based nanofibrous mats for bacterial inhibition. Li W, Li X, Chen Y, et al. Carbohydr. Polym. 92(2), 2232-8, (2013)

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Calcium alginate beads encapsulated PMMA-g-CS nano-particles for α-chymotrypsin immobilization. Abd El-Ghaffar MA and Hashem MS Carbohydr. Polym. 92(2), 2095-102, (2013)

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Straw N-halamines: evaluation in single and multistage filtration systems. Ahmed Ael-S, Cavalli G, Bushell ME, et al. Carbohydr. Polym. 92(2), 1934-41, (2013)

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Alginate-dependent gene expression mechanism in Sphingomonas sp. strain A1. Hayashi C, Takase R, Momma K, et al. J. Bacteriol. 196(14), 2691-700, (2014)

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Gelatine enhances drug dispersion in alginate bilayer film via the formation of crystalline microaggregates. Thu HE and Ng SF Int. J. Pharm. 454(1), 99-106, (2013)

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Comparison of ionic and non-ionic drug release from multi-membrane spherical aerogels. Veronovski A, Knez Z, and Novak Z Int. J. Pharm. 454(1), 58-66, (2013)

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Baicalein and hydroxypropyl-γ-cyclodextrin complex in poloxamer thermal sensitive hydrogel for vaginal administration. Zhou Q, Zhong L, Wei X, et al. Int. J. Pharm. 454(1), 125-34, (2013)

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Whey protein and alginate hydrogel microparticles for insulin intestinal absorption: evaluation of permeability enhancement properties on Caco-2 cells. Déat-Lainé E, Hoffart V, Garrait G, et al. Int. J. Pharm. 453(2), 336-42, (2013)

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Biocomposite scaffolds containing chitosan/alginate/nano-silica for bone tissue engineering. Sowjanya JA, Singh J, Mohita T, et al. Colloids Surf. B Biointerfaces 109, 294-300, (2013)

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Nanoparticles with surface antibody against CD98 and carrying CD98 small interfering RNA reduce colitis in mice. Xiao B, Laroui H, Viennois E, et al. Gastroenterology 146(5), 1289-300.e1-19, (2014)

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Efficient ethanol production from brown macroalgae sugars by a synthetic yeast platform. Enquist-Newman M, Faust AM, Bravo DD, et al. Nature 505(7482), 239-43, (2014)

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Assessment of the ecological security of immobilized enzyme remediation process with biological indicators of soil health. Zhang Y, Dong X, Jiang Z, et al. Environ. Sci. Pollut. Res. Int. 20(8), 5773-80, (2013)

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Vacuum-assisted wound closure versus alginate for the treatment of deep perivascular wound infections in the groin after vascular surgery. Monsen C, Wann-Hansson C, Wictorsson C, et al. J. Vasc. Surg. 59(1), 145-51, (2014)

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Safety and efficacy of ethylenediaminetetraacetic acid for removing microcapsules. Ren M, Liu R, Lv B, et al. J. Surg. Res. 183(1), 442-9, (2013)

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Combined hydrogels that switch human pluripotent stem cells from self-renewal to differentiation. Dixon JE, Shah DA, Rogers C, et al. Proc. Natl. Acad. Sci. U. S. A. 111(15), 5580-5, (2014)

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Optical properties of water soluble CdSe quantum dots modified by a novel biopolymer based on sodium alginate. Bardajee GR and Hooshyar Z Spectrochim. Acta. A. Mol. Biomol. Spectrosc. 114, 622-6, (2013)

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The dye or humic acid water treatment and membrane fouling by polyaluminum chloride composited with sodium alginate in coagulation-ultrafiltration process. Wang Y, Zhang F, Chu Y, et al. Water Sci. Technol. 67(10), 2202-9, (2013)

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Uncoupling reproduction from metabolism extends chronological lifespan in yeast. Nagarajan S, Kruckeberg AL, Schmidt KH, et al. Proc. Natl. Acad. Sci. U. S. A. 111(15), E1538-47, (2014)

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Optimization of sustained release matrix tablet of metoprolol succinate using central composite design. Li L, Sun H, Gao J, et al. Pak. J. Pharm. Sci. 26(5), 929-37, (2013)

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Kinetics of fungal extracellular alpha-amylase from Fusarium solani immobilized in calcium alginate beads. Kumar D, Muthukumar M, and Garg N J. Environ Biol. 33(6), 1021-5, (2012)

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Biosorption of lead by Kluyveromyces marxianus immobilized in alginate beads. Subhashini SS, Velan M, and Kaliappan S J. Environ Biol. 34(5), 831-5, (2013)

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A simple technique for tracking individual spore and gametophyte development in Adiantum lunulatum Burm. f. using modified extra thin alginate film technique. Sareen B, Bhattacharya A, Sharma M, et al. Indian J. Exp. Biol. 52(8), 820-4, (2014)

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Development of alginate-reinforced chitosan nanoparticles utilizing W/O nanoemulsification/internal crosslinking technique for transdermal delivery of rabeprazole. Ahmed TA and El-Say KM Life Sci. 110(1), 35-43, (2014)

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Preparation and properties of a pH sensitive carrier based on three kinds of polymer blend to control the release of 5-amino salicylic acid. Dong Y, Zhou Z, Ding H, et al. Pharm. Dev. Technol. 19(8), 960-7, (2014)

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Cesium accumulation of Rhodococcus erythropolis CS98 strain immobilized in hydrogel matrices. Takei T, Yamasaki M, and Yoshida M J. Biosci. Bioeng. 117(4), 497-500, (2014)

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Preparation and in vitro characterization of glibenclamide-loaded alginate hexyl-amide beads: a novel drug delivery system to improve the dissolution rate. Khames A, Abdelazeem AH, Habash M, et al. Pharm. Dev. Technol. 19(7), 881-90, (2014)

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Synthesis and characterization of new derivatives of alginic acid and evaluation of their iron(III)-crosslinked beads as potential controlled release matrices. Abulateefeh SR, Khanfar MA, Al Bakain RZ, et al. Pharm. Dev. Technol. 19(7), 856-67, (2014)

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Design and characterization of chitosan-alginate microspheres for ocular delivery of azelastine. Shinde UA, Shete JN, Nair HA, et al. Pharm. Dev. Technol. 19(7), 813-23, (2014)

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Stability of canola oil encapsulated by co-extrusion technology: effect of quercetin addition to alginate shell or oil core. Waterhouse GI, Wang W, and Sun-Waterhouse D Food Chem. 142, 27-38, (2014)

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Production of phloroglucinol by Escherichia coli using a stationary-phase promoter. Jung KH, Bang SH, Oh TK, Park HJ. Biotechnol. Lett., (2011)

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