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A0699 Sigma

Activin Receptor IA human

>95% (SDS-PAGE), recombinant, expressed in NSO cells, lyophilized powder

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Properties

Related Categories Activins, Activins and Inhibins, Cell Biology, Cell Signaling and Neuroscience, Cytokines and Growth Factors,
recombinant   expressed in NSO cells
assay   >95% (SDS-PAGE)
form   lyophilized powder
impurities   endotoxin, tested
storage temp.   −20°C
Gene Information   human ... ACVR1(90)

Description

Physical form

Lyophilized from a 0.2 μm filtered solution in phosphate buffered saline.

Biochem/physiol Actions

Activin receptor IA/Fc chimera does not bind directly to activin or inhibin but will associate with the type II receptor-activin complex and initiate signal transduction. Activin isoforms are members of the TGF-β superfamily that bind to heteromeric complexes of type I and type II serine/threonine kinase receptors, both of which are essential for signal transduction. Human, murine, and bovine type IA activin receptors demonstrate greater than 98% homology.

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Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
3

Documents

Certificate of Analysis

Certificate of Origin

Protocols & Articles
Peer-Reviewed Papers
15

References

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