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A0783 Sigma

N-Acetyl-L-proline

  • CAS Number 68-95-1

  • Empirical Formula (Hill Notation) C7H11NO3

  • Molecular Weight 157.17

  •  EC Number 200-698-9

  •  MDL number MFCD00020837

  •  PubChem Substance ID 24890453

  •  eCl@ss 32160406

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Properties

Related Categories A - H, Amino Acids, Biochemicals and Reagents, Modified Amino Acids
InChI Key   GNMSLDIYJOSUSW-LURJTMIESA-N
storage temp.   2-8°C

Description

Biochem/physiol Actions

N-Acetyl-L-proline, an analog of the COOH-terminal dipeptide portion of preferred angiotensin-converting enzyme substrates, is use to probe the active site of angiotensin-converting enzyme(s). N-Acetyl-L-proline may be used to to identify, differentiate and characterized N-acyl-amino acid amidohydrolase(s)/aminoacylase(s). N-Acetyl-L-proline is used to study the physicochemical parameters of prolines.

N-acetyl-L-proline is an analog of the COOH-terminal dipeptide portion of preferred substrates of angiotensin-converting enzyme (ACE). It may be used in studies of the binding of substrates and inhibitors by ACE and to differentiate the specificities of various aminoacylases.

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Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
3
Protocols & Articles
Peer-Reviewed Papers
15

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