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A0804 Sigma

Atrial Natriuretic Peptide fragment 4-24 frog

≥97% (HPLC)

Synonym: ANF 4-24, fANP-21

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Properties

Related Categories Cell Biology, Cell Signaling and Neuroscience, Guanylate Cyclase Activators, Miscellaneous Peptides, Natriuretic Peptides,
InChI Key   ICYRDBKHDKQDON-SMFLCKQOSA-N
assay   ≥97% (HPLC)
storage temp.   −20°C
Gene Information   African clawed frog ... anf-A(394320)

Description

Amino Acid Sequence

Cys-Phe-Gly-Ser-Arg-Ile-Asp-Arg-Ile-Gly-Ala-Gln-Ser-Gly-Met-Gly-Cys-Gly-Arg-Arg-Phe [Disulfide bridge: 4—20]

Biochem/physiol Actions

Atrial natriuretic peptide (ANP) is synthesized in myoendocrine cells of the heart from which it is released into the circulation. It exerts natriuretic, diuretic, and vasodilatory effects through stimulation of guanylate cyclase-linked NPR-A receptors. It plays an important role in blood volume and blood pressure homeostasis.

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Amplified Detection

All labs need water
Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
3

Documents

Certificate of Analysis

Protocols & Articles

Articles

Antihypertensive Agents

Download BioFiles v7 n5 (3.18 Mb PDF) Back to Pharmaceutical Drugs and Drug Candidates homepage
Sami Barghshoon
BioFiles v7 n5, 2012, 5–20
Keywords: AGE, Antihypertensives, Cardiovascular, Clinical, Diuretics, Pharmaceutical, Reductions

Peer-Reviewed Papers
15

References

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