• USA Home
  • A0972 - Apolipoprotein A-II from human plasma

EMAIL THIS PAGE TO A FRIEND
A0972 Sigma

Apolipoprotein A-II from human plasma

≥95% (SDS-PAGE), buffered aqueous solution

Synonym: Apo A-II

Purchase

Description

Application

Apo A-II constitutes ~20% of the protein moiety of high density lipoprotein (HDL).

Biochem/physiol Actions

Unlike Apo A-I, Apo A-II possesses no activating properties for lectin-cholesterol acyltransferase (LCAT). Furthermore, it was found that Apo A-II inhibits the activation of LCAT by Apo A-I.

General description

Forms dimers in aqueous solutions with an association constant of 5 × 104 M-1. The association is accompanied by an enhancement of ~35% in α-helical content.

Physical form

Solution in 10 mM ammonium bicarbonate.

Price and Availability


All labs need water
Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
3

Documents

Certificate of Analysis

Certificate of Origin

Protocols & Articles

Articles

Cholesterol Transport

Since cholesterol is a water-insoluble molecule it must be packaged for transport within the plasma. The particles that package cholesterol, cholesteryl esters, and triglycerides for transport, are c...
BioFiles 2007, 2.7, 13.
Keywords: Esterifications, Ligands

Plasma Derived Proteins and Enzymes

Despite their complexity, blood and plasma are abundant biological resources for the discovery of drug targets and biomarkers for human disease. It is estimated that plasma may contain as many as 40,...
BioFiles 2006, 1.5, 2.
Keywords: Applications, Gas chromatography, Type

Peer-Reviewed Papers
15

References

Set your institution to view full text papers.
Related Products

Technical Service:

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Bulk Ordering & Pricing:

Need larger quantities for your development, manufacturing or research applications?