|Related Categories||A-AM, Adenosines/P2 Nucleotide Receptor - Agonists, Adenosines/P2 Nucleotide Receptors (Purinergics), Agonists, Bioactive Small Molecules,|
|storage condition||protect from light|
|solubility||0.1 M acetic acid: soluble12 mM|
|Gene Information||rat ... Adora1(29290)|
Potent aqueous-soluble A1 adenosine receptor agonist.
Certificate of Analysis
There are four known subtypes of adenosine receptors, referred to as A1, A2A, A2B and A3. All are members of the superfamily of G protein-coupled receptors and each bears the characteristic motif of ...
Keywords: Atomic absorption spectroscopy, Cancer, Cardiovascular, Diabetes, Diseases, Gene expression, Inflammation, Neurotransmitters, Substitutions, Transduction
Differential effects of adenosine receptor antagonists injected intrathecally on antinociception induced by morphine and beta-endorphin administered intracerebroventricularly in the mouse. Suh HW, Song DK, and Kim YH Neuropeptides 31(4), 339-44, (1997)
Reduction of postischemic brain damage and memory deficits following treatment with the selective adenosine A1 receptor agonist. Von Lubitz DK, Beenhakker M, Lin RC, et al. Eur. J. Pharmacol. 302(1-3), 43-8, (1996)
Differential effects of the adenosine A1 receptor agonist adenosine amine congener on renal, femoral and carotid vascular conductance in preterm fetal sheep. Booth LC, Tummers L, Jensen EC, et al. Clin. Exp. Pharmacol. Physiol. 35(11), 1316-20, (2008)
A1 adenosine receptor upregulation and activation attenuates neuroinflammation and demyelination in a model of multiple sclerosis. Tsutsui S, Schnermann J, Noorbakhsh F, et al. J. Neurosci. 24(6), 1521-9, (2004)
The adenosine A1 receptor agonist adenosine amine congener exerts a neuroprotective effect against the development of striatal lesions and motor impairments in the 3-nitropropionic acid model of neurotoxicity. Blum D, Gall D, Galas MC, et al. J. Neurosci. 22(20), 9122-33, (2002)
Lack of central effects of peripherally administered adenosine A(1) agonists on synaptic transmission in the rat hippocampus. Gervitz LM, Lutherer LO, Hamilton ME, et al. Brain Res. 951(1), 141-5, (2002)
Vasodilator responses to adenosine and hyperemia are mediated by A(1) and A(2) receptors in the cat vascular bed. Bivalacqua TJ, Champion HC, Lambert DG, et al. Am. J. Physiol. Regul. Integr. Comp. Physiol. 282(6), R1696-709, (2002)
Protection against ischemic damage by adenosine amine congener, a potent and selective adenosine A1 receptor agonist. Von Lubitz DK, Lin RC, Bischofberger N, et al. Eur. J. Pharmacol. 369(3), 313-7, (1999)
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