EMAIL THIS PAGE TO A FRIEND
A1471 Sigma

A-85783

Synonym: (R)-6-(4-Fluorophenyl)-N,N-dimethyl-3-[3-(3-pyridinyl)-1H,3H-pyrrolo[1,2-c]thiazol-7-yl]carbonyl-1H-indole-1-carboxamide

Purchase

Properties

Related Categories Abbott, Approved Therapeutics/Drug Candidates, Bioactive Small Molecules, Cell Biology, Cell Signaling and Neuroscience,
InChI Key   YGUVFPOGHIKVPP-MUUNZHRXSA-N
mp   185.3-186.5 °C(lit.)
solubility   DMSO: 13 mg/mL
  H2O: insoluble
storage temp.   2-8°C

Description

Biochem/physiol Actions

Potent and selective platelet-activating factor (PAF) receptor antagonist.

General description

Shown to be effective both in vivo and in vitro. A-85783 is neutral and lipophilic and has been shown to competitively and reversibly inhibit [3H]PAF binding to rabbit platelet membranes as well as block PAF-induced serotonin release from rabbit platelets.

Legal Information

Sold under license from Abbott Laboratories.

Features and Benefits

This compound was developed by Abbott. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

Price and Availability


Better Together

Discover your Target

All labs need water
Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
3
Protocols & Articles
Related Products

Technical Service:

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Bulk Ordering & Pricing:

Need larger quantities for your development, manufacturing or research applications?