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A1594 Sigma

Anti-Activin A antibody produced in goat

affinity isolated antibody, lyophilized powder

Properties

Related Categories AC-AC, Activins, Activins and Inhibins, Alphabetical Index, Antibodies,
species reactivity   human
application(s)   ELISA: suitable
  immunohistochemistry (formalin-fixed, paraffin-embedded sections): 5-15 μg/mL
  neutralization: suitable
  western blot: 0.1 μg/mL
clone   polyclonal
antibody form   affinity isolated antibody
form   lyophilized powder
storage temp.   −20°C
Gene Information   human ... INHBA(3624)
biological source   goat
recombinant   expressed in goat
conjugate   unconjugated
Featured Industry   Research Pathology

Description

Immunogen

recombinant human activin A expressed in CHO cells.

General description

Activins are members of the TGF-β family. Activins are dimeric proteins composed of two beta subunits. Acitivn A contains two β A subunits. Activins bind to the Type II Activin receptor triggering phosphorylation of Type I Acitivn receptor (ALK4) and activation of downstream pathways such as proliferation and apoptosis.

Goat anti-activin A recognizes recombinant human activin A by direct ELISA, immunoblotting and immunohistochemistry.

The antibody will neutralize the biological activity of recombinant human activin A.

Physical form

Lyophilized from 0.2 μm-filtered solution in phosphate buffered saline containing carbohydrates.

Application

Anti-Activin A antibody can be used for immunohistochemistry (5-15 μg/mL), western blot (0.1 μg/mL) and neutralization assays.

Price and Availability


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