|Related Categories||Biochemicals and Reagents, Coenzyme A and Other Acyl Transfer Reagents, Cofactors, Core Bioreagents, Enzymes, Inhibitors, and Substrates,|
Substrate for acetoacetyl-CoA thiolase EC 22.214.171.124; Role in the biosynthesis of nonactin.
Acetoacetyl coenzyme A (Acetoacetyl-CoA) may be used as a substrate for a number of enzymes including; acetoacetyl-CoA thiolase (EC 2.3.1) which produces acetyl-CoA in reverse condensation reaction and (3-Hydroxy-3-methylglutar
Tandem Mass Spectrometry data independently generated by Scripps Center for Metabolomics is available to view or download in PDF. A1625.pdf Tested metabolites are featured on Scripps Center for Metabolomics METLIN Metabolite Database. To learn more, visit sigma.com/metlin.
Unprecedented acetoacetyl-coenzyme A synthesizing enzyme of the thiolase superfamily involved in the mevalonate pathway. Okamura E, Tomita T, et al. Proc. Natl. Acad. Sci. U. S. A. 107, 11265-11270, (2010)
Stimulation of hepatic cholesterol biosynthesis by fatty acids. Effects of oleate on cytoplasmic acetoacetyl-CoA thiolase, acetoacetyl-CoA synthetase and hydroxymethylglutaryl-CoA synthase. W.H. Salam et al. Biochem. J. 258, 563, (1989)
C.A. Clark J. Chem. Soc. Chem. Commun., 1568, (1985)
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