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A1774 Sigma

Amikacin disulfate salt

potency: 674-786 μg per mg (as amikacin base)

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Properties

Related Categories A - K, Aminoglycosides, Antibacterial, Antibiotics, Antibiotics A to Z,
biological source   from synthetic
material   white to off-white
InChI Key   FXKSEJFHKVNEFI-GCZBSULCSA-N
form   powder
potency   674-786 μg per mg (as amikacin base)
shelf life   2 yr
mol wt   mol wt 781.76 g/mol
pH   2.0-4.0 (1% in water)
solubility   H2O: soluble50 mg/mL
Mode of action   protein synthesis | interferes
antibiotic activity spectrum   Gram-negative bacteria
  mycobacteria
storage temp.   2-8°C

Description

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

Application

Amikacin is an aminoglycoside antibiotic commonly used in the treatment of drug-resistant mycobacteria . It is used to study organism-directed delivery of antibiotics as well as drug resistance .

Biochem/physiol Actions

Amikacin prevents bacterial protein synthesis by binding to the 30S ribosome subunit and inducing mRNA misreading.

Price and Availability

Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
2
RTECS 
WK1961200
Protocols & Articles
Peer-Reviewed Papers
15

References

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