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A1848 Sigma

Activated Leukocyte Cell Adhesion Molecule/Fc Chimera human

>95% (SDS-PAGE), recombinant, expressed in mouse NSO cells, lyophilized powder

Synonym: ALCAM, CD166, KG-CAM, MEMD, SC-1/DM-GRASP/BEN

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Properties

Related Categories Auxiliary Proteins, Biochemicals and Reagents, Other, Proteins and Derivatives
recombinant   expressed in mouse NSO cells
assay   >95% (SDS-PAGE)
form   lyophilized powder
mol wt   calculated mol wt 83.5 kDa
  mol wt ~120 kDa by SDS-PAGE (reducing)
impurities   endotoxin, tested
storage temp.   −20°C
Gene Information   human ... ALCAM(214)

Description

Analysis Note

Measured by its ability to block adhesion of HUT-78, a human cutaneous T cell lymphoma, to immobilized recombinant human CD6/Fc protein.

Biochem/physiol Actions

Type I membrane glycoprotein. Member of the immunoglobulin supergene family.

Other Notes

Extracellular domain of human ALCAM (residues 1-526) fused to carboxy-terminal histidine-tagged Fc portion of human IgG1.

Physical form

Lyophilized from a 0.2 μm filtered solution of phosphate buffered saline.

Price and Availability

Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
3
Protocols & Articles
Peer-Reviewed Papers
15

References

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