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  • A2236 - Anti-AP2S1 (11-25) antibody produced in rabbit

A2236 Sigma

Anti-AP2S1 (11-25) antibody produced in rabbit

IgG fraction of antiserum, buffered aqueous solution

Synonym: Anti-AP-2 complex subunit sigma-1 isoform 1, Anti-AP17-δ, Anti-AP17, Anti-CLAPS2, CLASP2



Related Categories AO-AQ, Alphabetical Index, Antibodies, Primary Antibodies
species reactivity   human
application(s)   western blot: 1:500-1:2,000
clone   polyclonal
antibody form   IgG fraction of antiserum
form   buffered aqueous solution
mol wt   antigen mol wt ~17 kDa
shipped in   dry ice
storage temp.   −20°C
Gene Information   human ... AP2S1(1175)
biological source   rabbit
conjugate   unconjugated



synthetic peptide corresponding to amino acids 11-25 of human AP2S1

General description

Adaptor protein-2 (AP2) is a key constituent of clathrin-coated vesicles that mediates the endocytosis of cell membrane components such as G protein-coupled receptors (GPCRs). AP2 is a heterotetramer that consists of α, β, μ and σ subunits which bind to tyrosine- and dileucine-based motifs on membrane-associated cargo proteins. Mutations in AP2 σ subunit (AP2S1) have been linked to a calcium homeostasis disorder, familial hypocalciuric hypercalcemia type 3 (FHH3). Rabbit anti-AP2S1 (11-25) antibody is specific for human AP2S1 (11-25).

Physical form

Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 15 mM sodium azide.


Rabbit anti-AP2S1 (11-25) antibody can be used for western blot (1:500-1:2,000) analysis.

Yale Center for High Throughput Cell Biology IF-tested antibodies. Each antibody is tested by immunofluorescence against HUVEC cells using the Yale HTCB IF protocol. To learn more about the Sigma Life Science and Yale Center for High Throughput Cell Biology partnership, visit sigma.com/htcb-if.

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Safety Information

RIDADR  NONH for all modes of transport
WGK Germany  2
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