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A255 Sigma

A-77636 hydrochloride hydrate

≥98% (HPLC), solid

Synonym: (−)-(1R,3S)-3-Adamantyl-1-(aminomethyl)-3,4-dihydro-5,6-dihydroxy-1H-2-benzopyran hydrochloride hydrate

  • CAS Number 145307-34-2 (anhydrous)

  • Empirical Formula (Hill Notation) C20H27NO3 · HCl · xH2O

  • Molecular Weight 365.89 (anhydrous basis)

  •  PubChem Substance ID 24277883

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Properties

Related Categories A-AM, Agonists, Bioactive Small Molecule Alphabetical Index, Bioactive Small Molecules, Biochemicals and Reagents,
InChI Key   KNACNUUSUYTFDY-LIWDBWMRSA-N
assay   ≥98% (HPLC)
form   solid
storage condition   desiccated
  protect from light
color   white to off-white
solubility   H2O: >10 mg/mL
storage temp.   −20°C
Gene Information   human ... DRD1(1812)

Description

Biochem/physiol Actions

Potent, orally active D1 dopamine receptor agonist.

Caution

Hygroscopic, photosensitive, and oxygen-sensitive. Solutions should be freshly prepared.

Legal Information

Manufactured and sold under exclusive license from Abbott Laboratories.

LOPAC is a registered trademark of Sigma-Aldrich Co. LLC

Features and Benefits

This compound is also offered as part of Sigma′s Library of Pharmacologically Active Compounds (LOPAC®1280), a biologically annotated collection of high-quality, ready-to-screen compounds. Click here to learn more.

This compound is featured on the Dopamine Receptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Price and Availability


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Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
3

Documents

Certificate of Analysis

Protocols & Articles
Peer-Reviewed Papers
15

References

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