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A269 Sigma

Anti-A2A Adenosine Receptor antibody produced in rabbit

affinity isolated antibody, buffered aqueous solution

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Properties

Related Categories AD-AD, Alphabetical Index, Antibodies, Antibodies for Neurotransmission, Antibodies to Neurotransmitter Receptors,
species reactivity   human, canine
does not react with   rat
application(s)   immunohistochemistry (frozen sections): 1:100
  immunoprecipitation: suitable
  western blot: 1:2000
clone   polyclonal
antibody form   affinity isolated antibody
form   buffered aqueous solution
mol wt   antigen mol wt ~45 kDa
shipped in   dry ice
storage temp.   −20°C
Gene Information   human ... ADORA2A(135)
biological source   rabbit
conjugate   unconjugated

Description

Immunogen

Synthetic peptide (Ser-His-Gly-Asp-Met-Gly-Leu-Pro-Asp-Val-Glu-Leu-Leu-Ser-His-Glu-Leu-Lys) derived from amino acids 373-391 of the canine A2A adenosine receptor C-terminal domain.

General description

ADORA2A is an adenosine receptor and part of the G-protein coupled receptor family of proteins. ADORA2A is involved in regulating myocardial blood flow and dopamine release in the brain.

Anti-A2A Adenosine Receptor is specific for A2A adenosine receptor adenosine receptor subtype. By immunoblotting, it reacts strongly with canine A2A. However, it does not react with rat A2A. The antibody detects A2A adenosine receptor in human hippocampus by immunohistology and may be used for immunoprecipitation.

Physical form

Solution in phosphate buffered saline, containing 1 mg/ml BSA and 0.05% sodium azide.

Application

Rabbit anti-A2A adenosine receptor antibody can be used for western blot applications. The antibody can also be used for immunohistochemistry (1:100, frozen sections) and immunoprecipitation applications.

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Safety Information

Personal Protective Equipment  Eyeshields, Gloves, half-mask respirator (US), multi-purpose combination respirator cartridge (US)
RIDADR  NONH for all modes of transport
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Peer-Reviewed Papers
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