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  • A275 - Monoclonal Anti-Na+/K+ ATPase (α1 Subunit) antibody produced in mouse

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A275 Sigma

Monoclonal Anti-Na+/K+ ATPase (α1 Subunit) antibody produced in mouse

clone 9A-5, ascites fluid

Properties

Related Categories Alphabetical Index, Antibodies, Antibodies for Cell Biology, Antibodies to Ion Channels, Antibodies to Ion Pumps,
species reactivity   canine, rat, avian, human
application(s)   immunohistochemistry (frozen sections): 1:1,000
  indirect ELISA: suitable
clone   9A-5, monoclonal
antibody form   ascites fluid
isotype   IgG1
mol wt   antigen mol wt ~110 kDa
shipped in   dry ice
storage temp.   −20°C
Gene Information   human ... ATP1A1(476)
rat ... Atp1a1(24211)
biological source   mouse
conjugate   unconjugated

Description

Immunogen

rat kidney Na+/K+ ATPase.

General description

Epitope mapping studies indicate the antibody binds within the intracellular region at or near Asp-369 of the α subunit. Staining is consistent with the plasma membrane localization of Na+/K+ ATPase.

Mouse Monoclonal Anti-Na+/K+ ATPase (α1 Subunit) antibody localizes the Na+/ K+ ATPase α1 subunit in human, canine, rat and avian tissues.

Na+/K+ transporting ATPase subunit α1 is an ion transport pump critical for maintaining the gradient of Na and K ions across the plasma membrane.

Physical form

Solution in phosphate buffered saline containing 0.05% sodium azide.

Application

Mouse Monoclonal Anti-Na+/K+ ATPase (α1 Subunit) antibody has been used for immunohistochemical assays. It has also been used for immunolabeling assays to quantify the expression of proteins involved in cellular ion transport. Furthermore, the product is suitable for use in indirect ELISA.

Price and Availability


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