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A2805 Sigma

L-Amino Acid Oxidase from Crotalus durissus venom

ammonium sulfate suspension, 3-8 units/mg protein

Synonym: L-AAO, L-Amino acid: oxygen oxidoreductase (deaminating)

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Description

Packaging

Package size based on protein content

Unit Definition

One unit will oxidatively deaminate 1.0 μmole of L-phenylalanine per min at pH 6.5 at 37 °C. (L-Leucine is deaminated at the same rate at pH 7.8 at 37 °C.)

Physical form

Suspension in 3.2 M (NH4)2SO4 pH approx. 6

Application

L-amino acid oxidase (LAAO) is used to convert L-amino acids to their corresponding α-keto acids. Product A2805 is from Crotalus durissus venom. L-amino acid oxidase, from Sigma, has been used in leucine aminopeptidase (LAP) activity assays .

Biochem/physiol Actions

L-amino acid oxidase is involved in various metabolic pathways such as alanine and aspartate metabolism, methionine metabolism, valine, leucine and isoleucine degradation, tyrosine metabolism, phenylalanine metabolism, tryptophan metabolism, phenylalanine, tyrosine and tryptophan biosynthesis, and alkaloid biosynthesis . It is found in microorganisms and in animal tissue, especially in kidney and liver.

Price and Availability


All labs need water

Biomedical Applications
Safety & Documentation

Safety Information

Symbol 
GHS06  GHS06
Signal word 
Danger
Hazard statements 
Precautionary statements 
RIDADR 
UN 3462 6.1 / PGI
WGK Germany 
3
RTECS 
RQ8300000
Protocols & Articles

Articles

Ammonium Sulfate Suspensions - Technical Note

Note that for an ammonium sulfate suspension, most of the enzyme will be in solid form. It is likely that only negligible amounts of enzyme will be in the ammonium sulfate solution.
Keywords: Enzyme activity

Related Content

Enzymes & Proteins

Application Index | Enzyme Index | Substrate Index | Inhibitor Index | Cofactor Index | Lectin Index
Keywords: Cell signaling, Diagnostic, Drug discovery, Molecular biology

Peer-Reviewed Papers
15

References

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