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A2835 Sigma

Amyloid Protein Non-Aβ Component

≥80% (HPLC)

Synonym: NAC

  • CAS Number 154040-19-4

  • Empirical Formula (Hill Notation) C141H235N39O49

  • Molecular Weight 3260.61

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Description

Amino Acid Sequence

Glu-Gln-Val-Thr-Asn-Val-Gly-Gly-Ala-Val-Val-Thr-Gly-Val-Thr-Ala-Val-Ala-Gln-Lys-Thr-Val-Glu-Gly-Ala-Gly-Ser-Ile-Ala-Ala-Ala-Thr-Gly-Phe-Val

Other Notes

Fragment 61-95 of a 140-amino acid amyloid precursor known as NACP, or α-synuclein

Biochem/physiol Actions

Found in the insoluble core of amyloid plaque; forms fibrils via a nucleation-dependent polymerization mechanism

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All labs need water

Amicon Ultra Centrifugal Filters
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Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
3

Documents

Certificate of Analysis

Certificate of Origin

Protocols & Articles
Peer-Reviewed Papers
15

References

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