Apolipoprotein C-III from human plasma buffered aqueous solution

Properties

form	buffered aqueous solution
mol wt	mol wt 8.75 kDa
storage temp.	−20°C
Gene Information	human ... APOC3(345)

Description

Physical form

Solution in 10 mM ammonium bicarbonate.

Biochem/physiol Actions

Apolipoprotein C-III (apoC-III) is central in regulating the metabolism of triglyceride-rich lipoproteins. It is an inhibitor of lipoprotein lipase (LPL). Plasma levels of apoC-III are somewhat correlated to body mass index (BMI) and insulin sensitivity, and strongly correlated to levels of VLDL triglycerides.¹ Reduced levels of apoC-III lead to higher fatty acid uptake of plasma triglycerides into adipose tissue.

Price and Availability

Related Papers

1. Rate of production of plasma and very-low-density lipoprotein (VLDL) apolipoprotein C-III is strongly related to the concentration and level of production of VLDL triglyceride in male subjects with different body weights and levels of insulin sensitivity Cohn, J.S., et al. J. Clin. Endocrinol. Metab. 89, 3949-3955, (2004)

Documents

Certificate of Analysis

Certificate of Origin

Safety Information

Personal Protective Equipment	Eyeshields, Gloves, half-mask respirator (US), multi-purpose combination respirator cartridge (US)
WGK Germany	3

Technical information & documentation associated with this product is available in the Safety & Documentation tab.

Articles

Cholesterol Transport

Since cholesterol is a water-insoluble molecule it must be packaged for transport within the plasma. The particles that package cholesterol, cholesteryl esters, and triglycerides for transport, are c...
BioFiles 2007, 2.7, 13.
Keywords: Esterifications, Ligands