|form||buffered aqueous solution|
|mol wt||mol wt 8.75 kDa|
|Gene Information||human ... APOC3(345)|
Solution in 10 mM ammonium bicarbonate.
Apolipoprotein C-III (apoC-III) is central in regulating the metabolism of triglyceride-rich lipoproteins. It is an inhibitor of lipoprotein lipase (LPL). Plasma levels of apoC-III are somewhat correlated to body mass index (BMI) and insulin sensitivity, and strongly correlated to levels of VLDL triglycerides.1 Reduced levels of apoC-III lead to higher fatty acid uptake of plasma triglycerides into adipose tissue.
Since cholesterol is a water-insoluble molecule it must be packaged for transport within the plasma. The particles that package cholesterol, cholesteryl esters, and triglycerides for transport, are c...
BioFiles 2007, 2.7, 13.
Keywords: Esterifications, Ligands
1. Rate of production of plasma and very-low-density lipoprotein (VLDL) apolipoprotein C-III is strongly related to the concentration and level of production of VLDL triglyceride in male subjects with different body weights and levels of insulin sensitivity Cohn, J.S., et al. J. Clin. Endocrinol. Metab. 89, 3949-3955, (2004)
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