|Related Categories||A-AM, Antibiotics, Antibiotics A to Z, Antibiotics A-F, Bioactive Small Molecules,|
|Gene Information||human ... CAMK2A(815), CAMK2B(816)|
A calmodulin antagonist; inhibits Ca2+/calmodulin activated phosphodiesterase and myosin light chain kinase.
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analytical standard, for drug analysis
Cyclic nucleotide-regulated cation channels are classified into two principal subfamilies, the cyclic nucleotide-gated (CNG) channels and the hyperpolarization-activated cyclic nucleotide-gated (HCN)...
Keywords: Atomic absorption spectroscopy, Diseases, Gene expression, Ligands, Transduction
Platelet-derived growth factor-BB activates calcium/calmodulin-dependent and -independent mechanisms that mediate Akt phosphorylation in the neurofibromin-deficient human Schwann cell line ST88-14. Farrer RG, Farrer JR, and DeVries GH J. Biol. Chem. 288(16), 11066-73, (2013)
GABA induces the differentiation of small into large cholangiocytes by activation of Ca(2+) /CaMK I-dependent adenylyl cyclase 8. Mancinelli R, Franchitto A, Glaser S, et al. Hepatology 58(1), 251-63, (2013)
Calmodulin-sensitive adenylyl cyclases mediate AVP-dependent cAMP production and Cl- secretion by human autosomal dominant polycystic kidney cells. Pinto CS, Reif GA, Nivens E, et al. Am. J. Physiol. Renal Physiol. 303(10), F1412-24, (2012)
Dynamic secondary structural changes in Ca²⁺-saturated calmodulin upon interaction with the antagonist, W-7. Sasakura D, Nunomura W, and Takakuwa Y Biochem. Biophys. Res. Commun. 423(2), 360-5, (2012)
Characterization and expression of calmodulin gene during larval settlement and metamorphosis of the polychaete Hydroides elegans. Chen ZF, Wang H, and Qian PY Comp. Biochem. Physiol. B Biochem. Mol. Biol. 162(4), 113-9, (2012)
Interactions of Bordetella pertussis adenylyl cyclase toxin CyaA with calmodulin mutants and calmodulin antagonists: comparison with membranous adenylyl cyclase I. Schuler D, Lübker C, Lushington GH, et al. Biochem. Pharmacol. 83(7), 839-48, (2012)
[In vitro effect of N-(6-aminohexyl)-5-chloro-1-naphthalenesulfonamide on differentiation from human adipose-derived mesenchymal stem cells to endothelial cells]. Zhai YJ, Chen J, Zhang HG, et al. Zhongguo Yi Xue Ke Xue Yuan Xue Bao. 33(3), 306-12, (2011)
Roles of osmolality, calcium - Potassium antagonist and calcium in activation and flagellar beating pattern of sturgeon sperm. Alavi SM, Gela D, Rodina M, et al. Comp. Biochem. Physiol. A. Mol. Integr. Physiol. 160(2), 166-74, (2011)
Interrelationship between calmodulin (CaM) and H2O2 in abscisic acid-induced antioxidant defense in the seedlings of Panax ginseng. Parvin S, Lee OR, Sathiyaraj G, et al. Mol. Biol. Rep. 39(7), 7327-38, (2012)
Ca(2+)-related signaling and protein phosphorylation abnormalities play central roles in a new experimental model of electrical storm. Tsuji Y, Hojo M, Voigt N, et al. Circulation 123(20), 2192-203, (2011)
Deletion of the calmodulin-binding domain of Grb7 impairs cell attachment to the extracellular matrix and migration. García-Palmero I and Villalobo A Biochem. Biophys. Res. Commun. 436(2), 271-7, (2013)
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