Synonym: Anti-A4 Amyloid protein, Anti-ABETA, Anti-ABPP, Anti-AD1, Anti-APPI, Anti-Amyloid β A4 protein, Anti-Amyloid-β protein (ABP)
Popular Documents: Datasheet (PDF)
|Related Categories||AM-AN, Alphabetical Index, Antibodies, Antibodies for Alzheimer′s Disease, Antibodies for Neurobiology,|
|species reactivity||rat, human, mouse|
|application(s)||indirect ELISA: 0.2-0.4 μg/mL using β-amyloid peptide (22-35)|
|western blot: 0.25-0.5 μg/mL using β-amyloid peptide (1-40)|
|antibody form||affinity isolated antibody|
|form||buffered aqueous solution|
|mol wt||antigen mol wt ~4 kDa|
|shipped in||dry ice|
human ... APP(351)|
mouse ... App(11820)
rat ... App(54226)
synthetic peptide corresponding to amino acids 22-35 of human β-amyloid (1-40) fragment, conjugated to KLH. This sequence corresponds to amino acids 693-706 of the human amyloid precursor protein APP, and is identical in mouse and rat APP.
Proteolytic cleavage of the amyloid precursor protein (APP) produces the small fragment amyloid β peptide. Cleavage of APP occurs mostly at residue 40 but to a lesser extent residue 42. Aggregates of amyloid β peptide are found deposited in the brains of Alzheimer′s patients.1
Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 15 mM sodium azide and 1% bovine serum albumin.
The antibody specifically recognizes β-amyloid (22-35), β-amyloid (25-35), β-amyloid (1-40), and β-amyloid (1-42) and does not react with β-amyloid (32-35) by ELISA. The antibody detects β-amyloid (1-40) by immunoblotting.
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Certificate of Analysis
|Personal Protective Equipment||Eyeshields, Gloves, half-mask respirator (US), multi-purpose combination respirator cartridge (US)|
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Keywords: Buffers, Cell biology, Epigenetics, Immunohistochemistry, Immunoprecipitation, Molecular biology, Neuroscience, Western blot
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|A8978||Monoclonal Anti-β-Amyloid (13-28) antibody produced in mouse, ~2 mg/mL, clone BAM90.1, purified immunoglobulin, buffered aqueous solution|
|A8354||Monoclonal Anti-β-Amyloid antibody produced in mouse, ~2 mg/mL, clone NAB 228, purified immunoglobulin, buffered aqueous solution|
|A3981||Monoclonal Anti-β-Amyloid antibody produced in mouse, ~1.5 mg/mL, clone BAM-10, purified immunoglobulin, buffered aqueous solution|
|A5213||Monoclonal Anti-β-Amyloid antibody produced in mouse, clone BAM-10, ascites fluid|
|A8326||Anti-β-Amyloid Protein (1-40) antibody produced in rabbit, whole antiserum|
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