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A3357 Sigma

Anti-ADRBK1 (651-665) antibody produced in rabbit

IgG fraction of antiserum, buffered aqueous solution

Synonym: Anti-β-ARK1, Anti-β-Adrenergic receptor kinase 1, Anti-BARK1, Anti-GRK2

Properties

Related Categories AD-AD, Alphabetical Index, Antibodies, Antibodies for Cell Biology, Antibodies to G Proteins,
species reactivity   human
application(s)   indirect immunofluorescence: suitable
  western blot: 1:500-1:1,000
clone   polyclonal
antibody form   IgG fraction of antiserum
form   buffered aqueous solution
mol wt   antigen mol wt ~79 kDa
shipped in   dry ice
storage temp.   −20°C
Gene Information   human ... ADRBK1(156)
biological source   rabbit
conjugate   unconjugated

Description

Immunogen

synthetic peptide corresponding to amino acids 651-665 of human ADRBK1.

General description

ADRBK1 or GRK2 is a ubiquitous enzyme that is present in the cytoplasm. This enzyme is known to phosphorylate β-adrenergic and related G-protein coupled receptors (GPCRs). ADRBK1 has been implicated in the development of cardiac disorders. Rabbit anti-ADRBK1 (651-665) antibody binds to human ADRBK1 (651-665).

β-ARK functions as a G-protein coupled receptor kinase.

Physical form

Solution in 0.01 M phosphate buffered saline, pH 7.2, containing 15 mM sodium azide.

Application

Rabbit anti-ADRBK1 (651-665) antibody can be used for western blot (1:500-1:1,000) and indirect immunofluorescence assays.

Yale Center for High Throughput Cell Biology IF-tested antibodies. Each antibody is tested by immunofluorescence against HUVEC cells using the Yale HTCB IF protocol. To learn more about the Sigma Life Science and Yale Center for High Throughput Cell Biology partnership, visit sigma.com/htcb-if.

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