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A3782 Sigma

Albumin from human serum

lyophilized powder, Fatty acid free, Globulin free, ≥99% (agarose gel electrophoresis)

Synonym: HSA

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Properties

Related Categories Albumin, Bioactives and Supplements for Stem Cell Expansion, Bioactives/Supplements, Biochemicals and Reagents, Cell Biology,
assay   ≥99% (agarose gel electrophoresis)
form   lyophilized powder
mol wt   monomer calculated mol wt 66478 Da
impurities   HIV I and HIVII, HCV and HBsAg, tested negative
  ≤0.02% Fatty acids
solubility   H2O: soluble50 mg/mL
storage temp.   2-8°C
Gene Information   human ... ALB(213)

Description

Other Notes

View more information on human serum albumin.

Packaging

1, 5, 10 g in poly bottle

100, 500 mg in poly bottle

Application

Albumin was used to test its effect on the in vitro bactericidal activity of cefditoren against penicillin-resistant Streptococcus pneumonia. It has been clinically used in serious and often life-threatening conditions, such as shock and blood loss due to trauma, burns, and surgery. It was used also to test the effect of non-enzymatic glycation on the unfolding of human serum albumin.

Biochem/physiol Actions

Serum albumin functions as a carrier protein for steroids, fatty acids, and thyroid hormones, and is vital in regulating the colloidal osmotic pressures of blood. Albumin is also seen to bind to exogenous substances, particularly drugs (e.g., ibuprofen, warfarin), and strongly influence their pharmacokinetics. Oxidative stress leading to changes in the redox state of albumin has widely varied effects on its physiological function.

General description

Albumin is the most copious protein in blood plasma. Liver produces human albumin.

Price and Availability

Safety & Documentation

Safety Information

Personal Protective Equipment 
RIDADR 
NONH for all modes of transport
WGK Germany 
3

Documents

Certificate of Analysis

Certificate of Origin

Protocols & Articles

Articles

Lipid Induced Insulin Resistance

Obesity is a well-established risk factor for the development of insulin resistance. Obesity is associated with the increased deposition of lipids in non-adipose tissue with subsequent decreases in i...
Linda Stephenson, Ph.D.
Biofiles v6 n4, 9
Keywords: Angiogenesis, Antivirals, Apoptosis, Biological processes, Cardiovascular, Catalog, Catalysis, Cell culture, Cell proliferation, Deposition, Diabetes, Events, Gene expression, Growth factors, Hormones, Inflammation, Metabolism, Metabolites, Obesity, Phosphorylations, Physiological Processes, Reductions, Transcription, Transduction, Type

Related Content

Albumin in Cell Culture

Importance and uses of albumin in serum-free eucaryotic, including hybridoma and Chinese Hamster Ovary (CHO) cell cultures
Keywords: Cell culture, Culture media, Degradations, Hormones, Ligands, Oxidations, PAGE, Purification, Redox Reactions

Peer-Reviewed Papers
15

References

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