• USA Home
  • A4110 - Anti-APBB2 (706-720) antibody produced in rabbit

A4110 Sigma

Anti-APBB2 (706-720) antibody produced in rabbit

IgG fraction of antiserum, buffered aqueous solution

Synonym: Anti-Amyloid β (A4) precursor protein-binding, family B, member 2, Anti-FE65L1, Anti-FE65L



Related Categories AO-AQ, Alphabetical Index, Antibodies, Primary Antibodies
species reactivity   human
application(s)   western blot: 1:500-1:2,000
clone   polyclonal
antibody form   IgG fraction of antiserum
form   buffered aqueous solution
mol wt   antigen mol wt ~83 kDa
shipped in   dry ice
storage temp.   −20°C
Gene Information   human ... APBB2(323)
biological source   rabbit
conjugate   unconjugated



synthetic peptide corresponding to amino acids 706-720 of human APBB2

General description

APBB2 contains two phosphotyrosine binding domains and interacts with the Alzheimer protein APP.

Rabbit anti-APBB2 is specific for human APBB2 (706-720).

The gene APBB2 (amyloid β precursor protein binding family B member 2) is mapped to human chromosome 4p13.

Physical form

Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 15 mM sodium azide.


Rabbit anti-APBB2 can be used for western blot (1:500-1:2,000) assays.

Yale Center for High Throughput Cell Biology IF-tested antibodies. Each antibody is tested by immunofluorescence against HUVEC cells using the Yale HTCB IF protocol. To learn more about the Sigma Life Science and Yale Center for High Throughput Cell Biology partnership, visit sigma.com/htcb-if.

Features and Benefits

Antibody Bioguarantee
Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Biochem/physiol Actions

The gene APBB2 (amyloid β precursor protein binding family B member 2), also referred to as FE65-like 1, encodes an adaptor protein that binds to the cytoplasmic domain of β-amyloid precursor protein (βAPP) and processes it to form β-amyloid (Aβ). Over-expression of APBB2 leads to an accumulation of Aβ in senile plaques seen in patients with Alzheimer′s disease (AD). Mutations in this gene have been associated with AD.

Price and Availability

Antibody Explorer

Explore with Confidence
Safety & Documentation

Safety Information

Safety Information for this product is unavailable at this time.
Protocols & Articles

Related Content

Antibody Explorer | Buy Primary & Secondary Antibodies

Monoclonal and polyclonal primary antibodies are focused on cell biology, neurobiology and molecular biology. Secondary antibodies targeting multiple host’s IgG are conjugated to alkaline phosphatase...
Keywords: Amplification, Buffers, Cell biology, Enzyme-linked immunosorbent assay, Immunofluorescence, Immunohistochemistry, Immunoprecipitation, Molecular biology, Phosphorylations, Purification, Western blot

Peer-Reviewed Papers


Related Products

Technical Service:

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Bulk Ordering & Pricing:

Need larger quantities for your development, manufacturing or research applications?