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A4327 Sigma

Albumin from human serum

lyophilized powder, essentially protease free, ≥96% (agarose gel electrophoresis)

Synonym: HSA

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Properties

Related Categories Albumin, Biochemicals and Reagents, Human Serum Albumins, Proteins and Derivatives
assay   ≥96% (agarose gel electrophoresis)
form   lyophilized powder
mol wt   monomer calculated mol wt 66478 Da
impurities   HIV I and HIVII, HCV and HBsAg, tested negative
solubility   H2O: soluble 50 mg/mL
foreign activity   Alkaline phosphatase ≤0.001 unit/mg protein
  Peroxidase ≤0.001 unit/mg protein
  Protease ≤0.0001 unit/mg protein
storage temp.   2-8°C
Gene Information   human ... ALB(213)

Description

Other Notes

View more information on human serum albumin.

Packaging

1 g in glass bottle

500 mg in glass bottle

Preparation Note

Prepared from A1653

Application

Albumin was used to test its effect on the in vitro bactericidal activity of cefditoren against penicillin-resistant Streptococcus pneumonia. It has been clinically used in serious and often life-threatening conditions, such as shock and blood loss due to trauma, burns, and surgery.
It was used to test the effect of non-enzymatic glycation on the unfolding of human serum albumin. It was also used to test the two distinct pathways used by intestinal epithelial cells for HLA class II antigen processing.

Biochem/physiol Actions

Serum albumin functions as a carrier protein for steroids, fatty acids, and thyroid hormones, and is vital in regulating the colloidal osmotic pressures of blood. Albumin is also seen to bind to exogenous substances, particularly drugs (e.g., ibuprofen, warfarin), and strongly influence their pharmacokinetics. Oxidative stress leading to changes in the redox state of albumin has widely varied effects on its physiological function.

General description

Albumin is the most copious protein in blood plasma. Liver produces human albumin.

Price and Availability

Safety & Documentation

Safety Information

Personal Protective Equipment 
RIDADR 
NONH for all modes of transport
WGK Germany 
3

Documents

Certificate of Analysis

Certificate of Origin

Protocols & Articles
Peer-Reviewed Papers
15

References

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Description

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A9731 Albumin human, recombinant, expressed in rice, lyophilized powder, cell culture tested, low endotoxin, ≥96% (Excised bands analyzed by MS to yield total albumin content, PAGE)
08168 Timestrip Plus 8 °C

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