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  • A4469 - Monoclonal Anti-ACTR/AIB1 antibody produced in mouse

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A4469 Sigma

Monoclonal Anti-ACTR/AIB1 antibody produced in mouse

clone AX 15, ascites fluid

Properties

Related Categories AA - CA, AC-AC, Alphabetical Index, Antibodies, Antibodies for Cell Biology,
species reactivity   human
application(s)   immunoprecipitation: 15 μL using 500 μg of a BG-1 ovarian cell RIPA lysate.
  western blot (chemiluminescent): 1:500 using RIPA lysates of BG-1 ovarian cancer cells
clone   AX 15, monoclonal
antibody form   ascites fluid
isotype   IgG
mol wt   antigen mol wt 150 kDa
contains   0.035% sodium azide
  30% glycerol
shipped in   wet ice
storage temp.   −20°C
Gene Information   human ... NCOA3(8202)
biological source   mouse
conjugate   unconjugated

Description

Immunogen

GST fusion protein containing amino acids 605-1294 of human ACTR.

General description

ACTR associates with estrogen receptors in breast and ovarian cancers and stimulates transcription. Hence, ACTR has been implicated in the carcinogenesis of breast and ovarian tumors. Mouse monoclonal Anti-ACTR/AIB1 antibody recognizes human ACTR (150kD) and another doublet (110kD) by immunoblotting.

ACTR, a nuclear receptor coactivator, is also referred to as amplified in breast cancer 1 (AIB1), thyroid hormone receptor activator molecule-1 (TRAM-1), receptor-associated coactivator 3 (RAC3 and SRC3).

Physical form

The product is supplied as mouse ascites fluid, containing 30% glycerol and 0.035% sodium azide

Application

Mouse monoclonal can be used for immunoprecipitation (15μL using 500μg of a BG-1 ovarian cell RIPA lysate) and western blot (1:500, using RIPA lysates of BG-1 ovarian cancer cells) assays.

Price and Availability


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