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A4599 Sigma

L-Arginine monohydrochloride

PharmaGrade, Ajinomoto, EP, JP, USP, Manufactured under appropriate GMP controls for pharma or biopharmaceutical production, suitable for cell culture

Synonym: (S)-(+)-2-Amino-5-[(aminoiminomethyl)amino]pentanoic acid monohydrochloride

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Properties

Related Categories Amino Acids, Analytical/Chromatography, Biochemicals and Reagents, Pharmacopoeia, Pharmacopoeia A-Z,
Quality Level   GMP-COMPENDIA
biological source   from non-animal source
grade   EP
  JP
  USP
InChI Key   KWTQSFXGGICVPE-WCCKRBBISA-N
product line   PharmaGrade
assay   ≥98.5%
form   crystalline powder
mfr. no.   Ajinomoto
impurities   endotoxin, heavy metals, residual solvents, tested
solubility   H2O: soluble100 mg/mL
suitability   suitable for cell culture
foreign activity   cytotoxicity, tested

Description

Biochem/physiol Actions

Substrate of nitric oxide synthase, which is converted to citrulline and nitric oxide (NO). Induces insulin release by a nitric oxide-dependent mechanism.

Linkage

To request the Enhanced Quality Product Documentation for this product, submit a PharmaGrade Product Information Request Form. Please note that access to the Enhanced Quality Product Documentation for this product requires a confidentiality disclosure agreement.

Application

L-Arginine is a non-essential amino acid. It is used as a cell culture media component for the commercial biomanufacture of therapeutic recombinant proteins and monoclonal antibodies. L-Arginine monohydrochloride is a modified version of L-Arginine with improved solubility.

General description

PharmaGrade products are manufactured under appropriate controls for use as a raw material in pharma or biopharmaceutical production. For more information on the PharmaGrade Program, visit sigma-aldrich.com/safc-pharmagrade.

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Laboratory Gloves
Safety & Documentation

Safety Information

Personal Protective Equipment 
RIDADR 
NONH for all modes of transport
WGK Germany 
2
Protocols & Articles

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Peer-Reviewed Papers
15

References

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