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A4660 Sigma

6-Thioguanine

Hybri-Max, 50 ×, γ-irradiated, lyophilized powder, BioXtra, suitable for hybridoma

Synonym: 2-Amino-6-mercaptopurine, 2-Amino-6-purinethiol

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Properties

Related Categories Cell Culture, Conditioned Media, Media Supplements and Reagents, Hybridoma Platform, Hybridoma Reagents, Reagents and Supplements,
grade   Hybri-Max
InChI Key   WYWHKKSPHMUBEB-UHFFFAOYSA-N
sterility   γ-irradiated
product line   BioXtra
assay   ~98%
form   lyophilized powder
concentration   50 ×
impurities   endotoxin, tested
mp   ≥300 °C(lit.)
suitability   suitable for hybridoma

Description

Application

Used in hybridoma formation applications as a selection agent.

Reconstitution

Reconstitute contents of vial with 10 ml sterile cell culture medium. Stock solution is sufficient to prepare 500 ml medium. Final working concentration: 30 μM 2-amino-6-mercaptopurine.

Biochem/physiol Actions

Ribosylated and phosphorylated by the same pathway as natural purine bases; as the nucleotide, inhibits a variety of cellular processes involved in nucleic acid synthesis. Has a long history as an effective treatment of leukemia.

Legal Information

Hybri-Max is a trademark of Sigma-Aldrich Co. LLC

Price and Availability


All labs need water
Safety & Documentation

Safety Information

Symbol 
GHS06  GHS06
Signal word 
Danger
Hazard statements 
Precautionary statements 
RIDADR 
UN 2811 6.1 / PGIII
WGK Germany 
3
RTECS 
UP0740000
Protocols & Articles
Peer-Reviewed Papers
15

References

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