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A4732 Sigma

Anti-AKT2 (121-135) antibody produced in rabbit

IgG fraction of antiserum, buffered aqueous solution

Synonym: Anti-PKBBETA, Anti-PRKBB, Anti-RAC-BETA, Anti-v-akt murine thymoma viral oncogene homolog 2

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Properties

Related Categories AE-AK, AKT Antibodies, AKT2 Antibodies, Alphabetical Index, Antibodies,
species reactivity   human
application(s)   indirect immunofluorescence: suitable
  western blot: 1:500-1:2,000
clone   polyclonal
antibody form   IgG fraction of antiserum
form   buffered aqueous solution
mol wt   antigen mol wt ~56 kDa
shipped in   dry ice
storage temp.   −20°C
Gene Information   human ... AKT2(208)
biological source   rabbit
conjugate   unconjugated

Description

Immunogen

synthetic peptide corresponding to amino acids 121-135 of human AKT2.

General description

Mouse Akt2 is involved in the phosphatidylinositide-3 (PI3K) / glycogen synthase kinase 3 (GSK3) signaling pathway which subsequently modulates the effects of brain-derived neurotrophic factor (BDNF) on mood stability, antidepressant effects and fear memory. Human AKT2 affects podocyte functions in chronic kidney disease and is also known to protect against aortic aneurysms. Rabbit Anti-AKT2 (121-135) antibody binds to human AKT2 (121-135).

Physical form

Solution in 0.01 M phosphate buffered saline, pH 7.2, containing 15 mM sodium azide.

Application

Rabbit Anti-AKT2 (121-135) antibody can be used for western blot (1:500-1:2,000) and indirect immunofluorescence applications.

Yale Center for High Throughput Cell Biology IF-tested antibodies. Each antibody is tested by immunofluorescence against HUVEC cells using the Yale HTCB IF protocol. To learn more about the Sigma Life Science and Yale Center for High Throughput Cell Biology partnership, visit sigma.com/htcb-if.

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Personal Protective Equipment  Eyeshields, Gloves, half-mask respirator (US), multi-purpose combination respirator cartridge (US)
RIDADR  NONH for all modes of transport
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Peer-Reviewed Papers
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