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A5232 Sigma

Anti-ALK (186-200) antibody produced in rabbit

IgG fraction of antiserum, buffered aqueous solution

Synonym: Anti-Anaplastic lymphoma kinase Ki-1, Anti-CD246, Anti-TFG/ALK

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Properties

Related Categories AL-AL, ALK, Alphabetical Index, Antibodies, Antibodies for Cell Biology,
species reactivity   human
application(s)   western blot: 1:500-1:2,000
clone   polyclonal
antibody form   IgG fraction of antiserum
form   buffered aqueous solution
mol wt   antigen mol wt ~176 kDa
shipped in   dry ice
storage temp.   −20°C
Gene Information   human ... ALK(238)
biological source   rabbit
conjugate   unconjugated

Description

Immunogen

synthetic peptide corresponding to amino acids 186-200 of human ALK.

General description

Anaplastic lymphoma receptor tyrosine kinase (ALK) is a tyrosine kinase member of the superfamily of insulin receptors. ALK modulates neurological development. Genetic alterations in ALK have been linked to neurological, lung and white blood cell cancers. Rabbit Anti-ALK (186-200) antibody binds to human ALK (186-200).

Physical form

Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 15 mM sodium azide.

Application

Rabbit Anti-ALK (186-200) antibody can be used for western blot applications at dilutions ranging from 1:500-1:2,000.

Yale Center for High Throughput Cell Biology IF-tested antibodies. Each antibody is tested by immunofluorescence against HUVEC cells using the Yale HTCB IF protocol. To learn more about the Sigma Life Science and Yale Center for High Throughput Cell Biology partnership, visit sigma.com/htcb-if.

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Safety Information

Personal Protective Equipment  Eyeshields, Gloves, half-mask respirator (US), multi-purpose combination respirator cartridge (US)
RIDADR  NONH for all modes of transport
Protocols & Articles

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Peer-Reviewed Papers
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