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A5376 Sigma

Acetylsalicylic acid

≥99.0%

Synonym: 2-Acetoxybenzoic acid, O-Acetylsalicylic acid, ASA, Aspirin

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Properties

Related Categories A to C, Application Index, Arachidonic Acid Cascade, Biochemicals and Reagents, Cancer Research,
InChI Key   BSYNRYMUTXBXSQ-UHFFFAOYSA-N
assay   ≥99.0%
form   powder
color   white
pKa (25 °C)   3.5
mp   134-136 °C(lit.)
solubility   H2O: soluble10 mg/mL at 37 °C(lit.)
  H2O: soluble3 mg/mL at 25 °C(lit.)
  ethanol: soluble50 mg/mL
  aqueous base: decomposes
absorption   ε1mM/230 nm, aqueous acid 466
  ε1mM/231 nm, aqueous base 409
  ε1mM/278 nm, aqueous acid 68
  ε1mM/298 nm, aqueous base 190
Gene Information   human ... ITGA2B(3674), ITGB3(3690), PTGS1(5742), PTGS2(5743)

Description

Frequently Asked Questions

Frequently Asked Questions are available for this Product.

Biochem/physiol Actions

Blocks the production of prostaglandins by inhibiting cyclooxygenase (prostaglandin H synthase), with greater selectivity toward the COX-1 isoform. The antithrombotic effect is due to the inhibition of COX-1 in platelets that blocks thromboxane production and platelet aggregation. Chemopreventive against colorectal and other solid tumors.

Packaging

1 kg in poly bottle

100, 250, 500 g in poly bottle

Price and Availability


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Safety & Documentation

Safety Information

Symbol 
GHS07  GHS07
Signal word 
Warning
Hazard statements 
Precautionary statements 
Personal Protective Equipment 
RIDADR 
NONH for all modes of transport
WGK Germany 
1
RTECS 
VO0700000
Flash Point(F) 
482 °F
Flash Point(C) 
250 °C
Protocols & Articles
Peer-Reviewed Papers
15

References

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