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A5376 Sigma

Acetylsalicylic acid

≥99.0%, crystalline

Synonym: 2-Acetoxybenzoic acid, O-Acetylsalicylic acid, ASA, Aspirin

Properties

Related Categories A to C, A-AM, Application Index, Arachidonic Acid Cascade, Bioactive Small Molecules,
assay   ≥99.0%
form   crystalline
color   white
pKa (25 °C)   3.5
mp   134-136 °C(lit.)
solubility   H2O: soluble10 mg/mL at 37 °C(lit.)
  H2O: soluble3 mg/mL at 25 °C(lit.)
  ethanol: soluble50 mg/mL
  aqueous base: decomposes
absorption   ε1mM/230 nm, aqueous acid 466
  ε1mM/231 nm, aqueous base 409
  ε1mM/278 nm, aqueous acid 68
  ε1mM/298 nm, aqueous base 190
Gene Information   human ... ITGA2B(3674), ITGB3(3690), PTGS1(5742), PTGS2(5743)

Description

Frequently Asked Questions

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Biochem/physiol Actions

Blocks the production of prostaglandins by inhibiting cyclooxygenase (prostaglandin H synthase), with greater selectivity toward the COX-1 isoform. The antithrombotic effect is due to the inhibition of COX-1 in platelets that blocks thromboxane production and platelet aggregation. Chemopreventive against colorectal and other solid tumors.

Packaging

1 kg in poly bottle

100, 250, 500 g in poly bottle

Price and Availability

Suggested Laboratory Gloves


Laboratory GlovesThis substance has been tested against several types of hand protection for CE compliance. Click below to find the recommended gloves for handling this product.




New TruPAGE™ Pre-cast Polyacrylamide Gels

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