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A5474 Sigma

L-Aspartic acid

PharmaGrade, Ajinomoto, EP, JP, USP, manufactured under appropriate GMP controls for Pharma or Biopharmaceutical production, suitable for cell culture

Synonym: (S)-(+)-Aminosuccinic acid, (S)-Aminobutanedioic acid

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Properties

Related Categories Amino Acids, Analytical/Chromatography, Biochemicals and Reagents, Pharmacopoeia, Pharmacopoeia A-Z,
Quality Level   GMP-COMPENDIA
biological source   from non-animal source
grade   EP
  JP
  USP
InChI Key   CKLJMWTZIZZHCS-REOHCLBHSA-N
product line   PharmaGrade
assay   ≥98.5%
form   crystalline powder
mfr. no.   Ajinomoto
impurities   endotoxin, heavy metals, trace metals, residual solvents, tested
mp   >300 °C (dec.)(lit.)
solubility   1 M HCl: 50 mg/mL
suitability   suitable for cell culture
  suitable for manufacturing use
foreign activity   cytotoxicity, tested
Gene Information   human ... CA1(759), CA2(760)
rat ... Grin2a(24409)

Description

Biochem/physiol Actions

Principal neurotransmitter for fast synaptic excitation.

Linkage

To request the Enhanced Quality Product Documentation for this product, submit a PharmaGrade Product Information Request Form. Please note that access to the Enhanced Quality Product Documentation for this product requires a confidentiality disclosure agreement.

Application

L-Aspartic acid is one of the 23 proteinogenic amino acids. It is a non-essential amino acid. It is used as a cell culture media component for the commercial biomanufacture of therapeutic recombinant proteins and monoclonal antibodies.

General description

PharmaGrade products are manufactured under appropriate controls for use as a raw material in pharma or biopharmaceutical production. For more information on the PharmaGrade Program, visit sigma-aldrich.com/safc-pharmagrade.

Price and Availability


Laboratory Gloves
Safety & Documentation

Safety Information

Personal Protective Equipment 
RIDADR 
NONH for all modes of transport
WGK Germany 
1
RTECS 
CI9098500
Protocols & Articles

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Peer-Reviewed Papers
15

References

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