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A5566 Sigma

Monoclonal Anti-α1-Acid Glycoprotein antibody produced in mouse

clone AGP-47, ascites fluid

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Properties

Related Categories AC-AC, Alphabetical Index, Antibodies, Antibodies for Cell Biology, Antibodies for Immune Cell Signaling and Blood,
species reactivity   human, baboon (weakly)
does not react with   bovine, canine
application(s)   dot blot: suitable
  indirect ELISA: suitable
  western blot: 1:10,000
clone   AGP-47, monoclonal
antibody form   ascites fluid
isotype   IgG1
contains   15 mM sodium azide
shipped in   dry ice
storage temp.   −20°C
Gene Information   human ... ORM1(5004)
biological source   mouse
conjugate   unconjugated

Description

Immunogen

human α1-acid glycoprotein (AGP).

General description

Alpha1-acid glycoprotein (AGP) is an acute-phase plasma protein that functions as a biomarker for inflammation. Increased levels of AGP have been linked to malignancies, trauma, rheumatoid arthritis, myocardial infarction and various other inflammatory disorders. Furthermore, this glycoprotein affects the pharmacokinetics of basic drugs that bind to AGP. Mouse monoclonal anti-alpha1-acid glycoprotein antibody binds to human AGP. The product may also weakly react with baboon AGP.

Recognizes an epitope located on the 44 kDa subunit of denatured-reduced AGP using the immunoblotting technique. It does not cross react with human serum amyloid P component, human haptoglobin, human C-reactive protein, and human IgG.

Application

Mouse monoclonal anti-alpha1-acid glycoprotein antibodies have been used at a dilution of 1:200 using human lung tissues. The antibody can also be used for dot-blot, indirect ELISA and western blot (1:10,000) assays.

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Safety Information

RIDADR  NONH for all modes of transport
WGK Germany  3
Protocols & Articles

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Antibody Explorer | Buy Primary & Secondary Antibodies

Monoclonal and polyclonal primary antibodies are focused on cell biology, neurobiology and molecular biology. Secondary antibodies targeting multiple host’s IgG are conjugated to alkaline phosphatase...
Keywords: Amplification, Buffers, Cell biology, Enzyme-linked immunosorbent assay, Immunofluorescence, Immunohistochemistry, Immunoprecipitation, Molecular biology, Phosphorylations, Purification, Western blot

Peer-Reviewed Papers
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References

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