|Related Categories||A-AM, Antibiotics, Antibiotics A to Z, Antibiotics A-F, Antibiotics by Application,|
|Gene Information||mouse ... Ahcy(269378)|
Used to study the roles of AMP-activated protein kinase (AMPK) in cell signaling.
Cell-permeable adenylate cyclase inhibitor; in detergent-dispersed rat brain preparation, IC50 = 30 μM. Clinically significant antiviral agent, especially against herpes simplex (HSV),1 by inhibition of DNA polymerase.
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DNA synthesis and methylation inhibitor
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crystalline, ≥90% (HPLC)
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Adenosine 3':5'-monophosphate (cAMP) modifies cell function in all eukaryotic cells, principally through the activation of cAMP-dependent protein kinase (PKA), but also through cAMP-gated ion channel...
Keywords: Catalysis, Cell proliferation, Detergents, Diabetes, Gene expression, Gluconeogenesis, Hormones, Ligands, Neurotransmission, Recombination, Transduction
Release of an ~55kDa fragment containing the actin-binding domain of β-spectrin by caspase-8 during FND-induced apoptosis depends on the presence of protein 4.1. Toporkiewicz M, Grzybek M, Meissner J, et al. Arch. Biochem. Biophys. 535(2), 205-13, (2013)
R-CVP versus R-CHOP versus R-FM for the initial treatment of patients with advanced-stage follicular lymphoma: results of the FOLL05 trial conducted by the Fondazione Italiana Linfomi. Federico M, Luminari S, Dondi A, et al. J. Clin. Oncol. 31(12), 1506-13, (2013)
The clinical characteristics and prognostic significance of MN1 gene and MN1-associated microRNA expression in adult patients with de novo acute myeloid leukemia. Xiang L, Li M, Liu Y, et al. Ann. Hematol. 92(8), 1063-9, (2013)
Sequential chemoimmunotherapy of fludarabine, mitoxantrone, and cyclophosphamide induction followed by alemtuzumab consolidation is effective in T-cell prolymphocytic leukemia. Hopfinger G, Busch R, Pflug N, et al. Cancer 119(12), 2258-67, (2013)
Treatment of children and adolescents with Hodgkin lymphoma without radiotherapy for patients in complete remission after chemotherapy: final results of the multinational trial GPOH-HD95. Dörffel W, Rühl U, Lüders H, et al. J. Clin. Oncol. 31(12), 1562-8, (2013)
Omega 3 fatty acids increase the chemo-sensitivity of B-CLL-derived cell lines EHEB and MEC-2 and of B-PLL-derived cell line JVM-2 to anti-cancer drugs doxorubicin, vincristine and fludarabine. Fahrmann JF and Hardman WE Lipids Health Dis. 12, 36, (2013)
Risk adopted allogeneic hematopoietic stem cell transplantation using a reduced intensity regimen for children with thalassemia major. Hussein AA, Al-Zaben A, Ghatasheh L, et al. Pediatr. Blood Cancer 60(8), 1345-9, (2013)
Busulfan, fludarabine, and alemtuzumab conditioning and unrelated cord blood transplantation in children with sickle cell disease. Radhakrishnan K, Bhatia M, Geyer MB, et al. Biol. Blood Marrow Transplant. 19(4), 676-7, (2013)
Busulfan plus fludarabine as a myeloablative conditioning regimen compared with busulfan plus cyclophosphamide for acute myeloid leukemia in first complete remission undergoing allogeneic hematopoietic stem cell transplantation: a prospective and multicenter study. Liu H, Zhai X, Song Z, et al. J. Hematol. Oncol. 6, 15, (2013)
Early-onset therapy-related myelodysplastic syndrome originating from prolonged myelosuppression after fludarabine-based therapy. Yamazaki S, Nakamura F, Nannya Y, et al. Intern. Med. 51(24), 3427-30, (2012)
Results of a randomized trial of chlorambucil versus fludarabine for patients with untreated Waldenström macroglobulinemia, marginal zone lymphoma, or lymphoplasmacytic lymphoma. Leblond V, Johnson S, Chevret S, et al. J. Clin. Oncol. 31(3), 301-7, (2013)
Effect of IFN-α on KC and LIX expression: role of STAT1 and its effect on neutrophil recruitment to the spleen after lipopolysaccharide stimulation. Pan H, Ma Y, Wang D, et al. Mol. Immunol. 56(1-2), 12-22, (2013)
A novel bioluminescent bacterial biosensor for measurement of Ara-CTP and cytarabine potentiation by fludarabine in seven leukaemic cell lines. Anderson E, Smith MA, Martin A, et al. Leuk. Res. 37(6), 690-6, (2013)
In vivo T-cell depletion with alemtuzumab in allogeneic hematopoietic stem cell transplantation: Combined results of two studies on aplastic anemia and HLA-mismatched haploidentical transplantation. Kanda Y, Oshima K, Kako S, et al. Am. J. Hematol. 88(4), 294-300, (2013)
Improved outcome in pediatric relapsed acute myeloid leukemia: results of a randomized trial on liposomal daunorubicin by the International BFM Study Group. Kaspers GJ, Zimmermann M, Reinhardt D, et al. J. Clin. Oncol. 31(5), 599-607, (2013)
Impact of hyperferritinemia on the outcome of reduced-intensity conditioning allogeneic hematopoietic cell transplantation for lymphoid malignancies. Barba P, Valcárcel D, Pérez-Simón JA, et al. Biol. Blood Marrow Transplant. 19(4), 597-601, (2013)
Prognostic impact of immune status and hematopoietic recovery before and after fludarabine, IV busulfan, and antithymocyte globulins (FB2 regimen) reduced-intensity conditioning regimen (RIC) allogeneic stem cell transplantation (allo-SCT). Le Bourgeois A, Lestang E, Guillaume T, et al. Eur. J. Haematol. 90(3), 177-86, (2013)
Rational design of non-nucleoside, potent, and orally bioavailable adenosine deaminase inhibitors: predicting enzyme conformational change and metabolism. Tadashi Terasaka et al J. Med. Chem. 48, 4750-3, (2005)
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