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A5971 Sigma

Anti-Water Channel Aquaporin 4 antibody produced in rabbit

lyophilized powder, affinity isolated antibody

Synonym: Anti-Mercurial-Insensitive Water Channel, Anti-AQP4, Anti-WCH4

Properties

Related Categories Alphabetical Index, Antibodies, Antibodies for Cell Biology, Antibodies to Aquaporin (Water) Channels, Antibodies to Ion Channels,
species reactivity   human, rat, mouse
application(s)   flow cytometry: suitable
  immunocytochemistry: suitable
  immunohistochemistry: suitable
  western blot: suitable
clone   polyclonal
antibody form   affinity isolated antibody
form   lyophilized powder
storage temp.   −20°C
Gene Information   human ... AQP4(361)
mouse ... Aqp4(11829)
rat ... Aqp4(25293)
biological source   rabbit
conjugate   unconjugated

Description

Immunogen

recombinant fusion protein corresponding to residues 249-323 of rat AQP4 fused to GST.

General description

AQP4 is an osmoreceptor that regulates water flow in the CNS. It is abundant in astrocytes, but is also weakly noticeable in pulmonary, intestinal, ocular and renal tissues. Rabbit Anti-Water Channel Aquaporin 4 antibody recognizes aquaporin 4 in human, mice and rats.

Physical form

Lyophilized from phosphate buffered saline, pH 7.4, containing 1% bovine serum albumin, and 0.05% sodium azide.

Application

Rabbit Anti-Water Channel Aquaporin 4 antibody can be used for immunohistochemical applications. The antibody can also be used for immunocytochemistry, western blot and flow cytometry applications.

Biochem/physiol Actions

Immunoprecipation and western blot analysis using HEK-293 cells that had been transfected with GFP-AQP4 was performed using rabbit anti-AQP4 as the primary antibody at 2μl/ml.

Price and Availability


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