• USA Home
  • A5973 - Amyloid-β-Protein Fragment 1-40, All D-Amino Acids

EMAIL THIS PAGE TO A FRIEND
A5973 Sigma

Amyloid-β-Protein Fragment 1-40, All D-Amino Acids

>70% (HPLC), lyophilized powder

Synonym: β-Amyloid (Aβ)[1-40, all D-amino acids]

Purchase

Properties

Related Categories Alzheimer′s Disease, Amyloid Precursor Proteins and Fragments, Amyloid beta Protein Fragments, Cell Biology, Cell Signaling and Neuroscience,
assay   >70% (HPLC)
form   lyophilized powder
mol wt   mol wt 4331
composition   Protein content, ~80%
solubility   H2O: soluble
storage temp.   −20°C
Gene Information   human ... APP(351)
mouse ... APP(11820)
rat ... APP(54226)

Description

Amino Acid Sequence

Asp-Ala-Glu-Phe-Arg-His-Asp-Ser-Gly-Tyr-Glu-Val-His-His-Gln-Lys-Leu-Val-Phe-Phe-Ala-Glu-Asp-Val-Gly-Ser-Asn-Lys-Gly-Ala-Ile-Ile-Gly-Leu-Met-Val-Gly-Gly-Val-Val

Application

Used in the study of plaques and tangles that occur in Alzheimer′s disease (AD) patients.

Biochem/physiol Actions

This D-amino acid peptide functions as a control useful in elucidating structural dependence of aggregation properties characteristic of the amyloid-β 1-40 peptide associated with plaque formation and Alzheimer′s disease.

Price and Availability


Amplified Detection

Free Webinar

Amicon Ultra Centrifugal Filters
Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
3

Documents

Certificate of Analysis

Certificate of Origin

Protocols & Articles

Articles

Alzheimer's Disease

Alzheimer's disease (AD) is the most common cause of dementia in the elderly and is characterized by gradual loss of cognitive functions. Hallmark pathohistological findings of AD include widespread ...
Carolyn L. Crankshaw
BioFiles v7 n2, 2011, 4–8
Keywords: Alzheimer Disease, Gene expression, Genetic, Genetics, Inflammation, Metabolism, Phosphorylations

Related Products

Technical Service:

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Bulk Ordering & Pricing:

Need larger quantities for your development, manufacturing or research applications?