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A6218 Sigma

Anti-ATM antibody, Mouse monoclonal

clone SYML6A10, purified from hybridoma cell culture

Synonym: Anti-Ataxia-Telangiectasia Mutated, Monoclonal Anti-ATM antibody produced in mouse

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Properties

Related Categories AA - CA, ATH-AZ, ATM, Alphabetical Index, Antibodies,
species reactivity   human
application(s)   immunocytochemistry: suitable
  microarray: suitable
  western blot: 1-2 μg/mL using total cell extract from a G-361 (human melanoma) cell line
clone   SYML6A10, monoclonal
antibody form   purified immunoglobulin
form   buffered aqueous solution
isotype   IgG1
mol wt   antigen mol wt ~350 kDa
shipped in   dry ice
storage temp.   −20°C
Gene Information   human ... ATM(472)
biological source   mouse
conjugate   unconjugated

Description

Immunogen

synthetic peptide corresponding to the C-terminal region of human ATM (amino acids 2581-2599, with N-terminally added cysteine) conjugated to KLH.

General description

Ataxia-Telangiectasia Mutated (ATM) is a member of the phosphatidylinositol 3-kinase (PI-3) family of kinases. It is activated in response to DNA damage such as double stranded breaks.

Mouse Monoclonal Anti-ATM antibody binds to human ATM.

Physical form

Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 15 mM sodium azide.

Application

Mouse Monoclonal Anti-ATM antibody can be used for western blot assays at 1-2μg/ml using G-361 cell extracts. The antibody can also be used for immunocytochemistry and microarray applications.

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