Synonym: Trasylol, Trypsin inhibitor (basic)
|Related Categories||AN-AZ, Bioactive Small Molecules, Biochemicals and Reagents, Cell Biology, Cell Signaling and Neuroscience,|
|mol wt||mol wt ~6,500|
|Gene Information||cow ... PTI(404172)|
Another commonly used unit of activity is the KIU (Kallikrein Inhibitor Unit).
1 TIU ∼ 1,300 KIU.
Protein determined by biuret.
Contains 5-10 TIU per mL solution.
One trypsin inhibitor unit (TIU) will decrease the activity of 2 trypsin units by 50% where one trypsin unit will hydrolyze 1.0 μmole of N-α-benzoyl-
Solution in 0.9% NaCl and 0.9% benzyl alcohol.
Aprotinin is a protein consisting of 58 amino acids, arranged in a single polypeptide chain that is crosslinked by three disulfide bridges.
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lyophilized powder, 3-8 TIU/mg solid, BioReagent, suitable for cell culture
synthetic, ≥85% (HPLC)
Certificate of Analysis
Certificate of Origin
|Personal Protective Equipment||Eyeshields, Gloves, half-mask respirator (US), multi-purpose combination respirator cartridge (US)|
2. SCOPE The scope of this procedure is all products that have a specification for Aprotinin activity.
Keywords: Enzymology, Extinction coefficient
Review: Biochemistry of aprotinin and aprotinin-like inhibitors. Gebhard, W. Res. Monogr. Cell Tissue Physiol. 12, 375, (1986)
Trautschold, I., et al. Biochem. Pharmacol. 16, 59, (1967)
Beynon, R.J. and Bond, J.S., ed. Proteolytic Enzymes: A Practical Approach, (1989), 247
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