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A6345 Sigma

N-Acetyl-Ile-Glu-Pro-Asp-7-amino-4-trifluoromethylcoumarin

97% (HPLC), powder

Synonym: Ac-IEPD-AFC

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Properties

Related Categories Apoptosis Enzymes, Apoptosis and Cell Cycle, Application Index, Biochemicals and Reagents, Cathepsin/Granzyme Inhibitors & Substrates,
InChI Key   HWXKKVLJPWMVLL-FGGUPADCSA-N
assay   97% (HPLC)
form   powder
color   white
solubility   DMSO/DMF: soluble20 mM
shipped in   dry ice
storage temp.   −20°C
Gene Information   human ... GZMB(3002)
mouse ... GZMB(171528)
rat ... GZMB(14939), RGD1561819(502004), RGD1562700(502007)

Description

Amino Acid Sequence

NAc-Ile-Glu-Pro-Asp-AFC

Application

Fluorogenic substrate for granzyme B.

Price and Availability


Amplified Detection

Flow Cytometry Instruments

Amicon Ultra Centrifugal Filters
Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
3
Protocols & Articles
Peer-Reviewed Papers
15

References

Related Products

related product

Product #

Description

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G9278 Granzyme B from mouse, ≥90% (SDS-PAGE), recombinant, expressed in Pichia pastoris, buffered aqueous solution, ≥10,000 units/mg protein
G1044 Monoclonal Anti-Granzyme B antibody produced in mouse, clone GrB7, tissue culture supernatant
CS1080 SensiZyme Granzyme B Activity Assay Kit, sufficient for 96 reactions (96-well plate)

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