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A6469 Sigma

Apelin-13 trifluoroacetate salt

≥95%

Synonym: Prepro-65-77-Apelin

  • Empirical Formula (Hill Notation) C69H111N23O16S · C2F3O2

  • Molecular Weight 1663.84

  •  PubChem Substance ID 329770894

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Properties

Related Categories Angiotensins, Approved Therapeutics/Drug Candidates, Bioactive Small Molecules, Cell Biology, Cell Signaling and Neuroscience,
InChI Key   IUOVYCLNUOUEHV-PDGAQFIRSA-N
assay   ≥95%
storage temp.   −20°C
Gene Information   human ... APLN(8862)

Description

Amino Acid Sequence

Gln-Arg-Pro-Arg-Leu-Ser-His-Lys-Gly-Pro-Met-Pro-Phe

Other Notes

Lyophilized from 0.1% TFA in H2O

Biochem/physiol Actions

Synthetic endogenous peptide agonist for the human APJ receptor, a putative receptor protein related to the angiotensin receptor (AT1). This peptide exerted an acidification-rate-promoting activity in CHO cells expressing the APJ receptor with a median effective concentration (EC50) value of 0.37 nM. Blocks HIV-1 and HIV-2 entry into cells expressing the APJ receptor.

Price and Availability


Amplified Detection

Neuroscience Grant Programm

Amicon Ultra Centrifugal Filters
Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
3

Documents

Certificate of Analysis

Protocols & Articles
Peer-Reviewed Papers
15

References

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