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A6508 Sigma

L-Aspartic acid β-hydroxamate

serine racemase inhibitor

Synonym: AAH, HDX, LAH

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Properties

Related Categories A - H, Amino Acids, Biochemicals and Reagents, Modified Amino Acids
InChI Key   ZBYVTTSIVDYQSO-REOHCLBHSA-N
storage temp.   −20°C

Description

Packaging

1 g in poly bottle

100 mg in poly bottle

Biochem/physiol Actions

L-Aspartic acid β-hydroxamate (AAH) is used as an inhibitor for the studying the specificity and kinetics of serine racemases. AAH has demonstrated antioxidant activity and competitive inhibition against angiotensin converting enzyme (ACE). L-Aspartate-β-hydroxamate was effective in promoting the editing activity of asparaginyl-tRNA synthetase (AsnRS) from Brugia malayi and Staphylococcus epidermidis. AAH was found to be cytotoxic against L5178Y leukemia cells but with lower tolerance in DBA/2 mice than the D-isomer.

L-Aspartic acid β-hydroxamate (AAH) is used as an inhibitor for the studying the specificity and kinetics of serine racemase(s) and angiotensin converting enzyme(s) (ACE).

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Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
3
Protocols & Articles
Peer-Reviewed Papers
15

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92210 Timestrip Plus 0 °C
06693 Timestrip Plus -20 °C

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