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A6850 Sigma

Azelaoyl PAF

10 mg/mL in ethanol

Synonym: 1-O-Hexadecyl-2-O-(9-carboxyoctanoyl)-sn-glyceryl-3-phosphocholine, 1-O-Hexadecyl-2-azelaoyl-sn-glycero-3-phosphocholine, hexadecyl azelaoyl phosphatidylcholine

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Properties

Related Categories AN-AZ, Bioactive Small Molecule Alphabetical Index, Bioactive Small Molecules, Cell Biology, Cell Signaling and Neuroscience,
InChI Key   ZDFOCDTXDPKJKA-WJOKGBTCSA-N
form   liquid
concentration   10 mg/mL in ethanol
shipped in   wet ice
storage temp.   −20°C

Description

Biochem/physiol Actions

Potent PPARγ agonist.

Application

Azelaoyl PAF is a potent PPARγ agonist. Azelaoyl PAF has been used to investigate whether peroxisome proliferator-activated receptors gamma agonists could play a role in the treatment of Friedreich′s ataxia, a neurodegenerative disease due to frataxin deficiency.

Features and Benefits

This compound is featured on the Nuclear Receptors (PPARs) page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

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Safety & Documentation

Safety Information

Symbol 
Signal word 
Danger
Hazard statements 
RIDADR 
UN1170 - class 3 - PG 2 - Ethanol
WGK Germany 
2
Flash Point(F) 
57.2 °F
Flash Point(C) 
14 °C

Documents

Certificate of Analysis

Certificate of Origin

Protocols & Articles
Peer-Reviewed Papers
15

References

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