Adenosine 3′,5′-cyclic monophosphate sodium salt monohydrate
≥98.0% (HPLC), powder
DOWNLOAD MSDS (PDF)Synonym: 3′,5′-Cyclic AMP sodium salt, cAMP-Na
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CAS Number 37839-81-9
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Empirical Formula (Hill Notation) C10H11N5NaO6P · H2O
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Molecular Weight 369.20
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Beilstein Registry Number 54612
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MDL number MFCD00069736
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PubChem Substance ID 24891151
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Popular Documents: Specification Sheet (PDF)
Properties
| Related Categories | A-AM, Bioactive Small Molecules, Cell Biology, Cell Signaling and Neuroscience, Cyclic Nucleotide Metabolism, |
| assay | ≥98.0% (HPLC) |
| form | powder |
| color | white |
| solubility | H2O: soluble50 mg/mL |
| storage temp. | −20°C |
Description
Application
Adenosine-3′,5′-cyclic monophosphate (cAMP) is an activator of cyclic-AMP-dependent protein kinase A (PKA). The cAMP/PKA signaling pathway has been shown to inhibit cell proliferation, induce differentiation and lead to apoptosis. Exogneous cAMP plays a role in the spontaneous activity and contraction of the heart muscle.
Biochem/physiol Actions
Naturally-occurring activator of cyclic-AMP-dependent protein kinase (PKA). cAMP is an important second messenger that is linked in many systems to neurotransmitter- or hormone-induced receptor stimulation. The cAMP/PKA signaling pathway has been shown to inhibit cell proliferation, induce differentiation and lead to apoptosis.
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from yeast, ≥99%
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