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A6970 Sigma

Monoclonal Anti-Acetylcholinesterase antibody produced in mouse

clone ZR3, purified immunoglobulin, buffered aqueous solution

Synonym: Monoclonal Anti-AChE

Properties

Related Categories AC-AC, Alphabetical Index, Antibodies, Antibodies for Neurobiology, Antibodies for Neurotransmission,
species reactivity   rabbit, rat, guinea pig, feline
does not react with   chicken, mouse, human
application(s)   immunohistochemistry: 1:1,000 using rat brain tissue
  immunoprecipitation: suitable
clone   ZR3, monoclonal
antibody form   purified immunoglobulin
form   buffered aqueous solution
isotype   IgG2b
shipped in   dry ice
storage temp.   −20°C
Gene Information   rat ... Ache(83817)
biological source   mouse
conjugate   unconjugated

Description

Immunogen

rat brain acetylcholinesterase.

General description

AcHE, also known as acetylcholine acetuhydrolase, is found localized to neuromuscular juntions where it is involved in synaptic signaling by degradation of acetylcholine.

Acetylcholinesterase (AChE) is an integral component of the cholinergic nervous system and a target of many toxic compounds including nerve agents and insecticides. Decreased AChE functions have been linked to neurodevelopmental disorders. Mouse monoclonal Anti-Acetylcholinesterase antibody recognizes acetylcholinesterase in rat, guinea pig, rabbit and feline tissues. The antibody does not recognize human, mouse or chicken antigens, and also does not cross react with butyryl-cholinesterase (BChE).

Physical form

Solution in 0.01 M phosphate buffered saline containing 1 mg/mL BSA and 0.05% sodium azide.

Application

Mouse monoclonal Anti-Acetylcholinesterase antibody can be used for immunohistochemistry (1:1,000) and immunoprecipitation applications.

Price and Availability

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