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A6981 Sigma

Acamprosate calcium

≥98% (HPLC), powder

Synonym: 3-(Acetylamino)-1-propanesulfonic acid calcium salt (2:1)

  • CAS Number 77337-73-6

  • Empirical Formula (Hill Notation) C5H10Ca0.5NO4S

  • Molecular Weight 200.24

  •  EC Number 278-665-3

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Properties

Related Categories A-AM, Agonists, Approved Therapeutics/Drug Candidates, Bioactive Small Molecule Alphabetical Index, Bioactive Small Molecules,
assay   ≥98% (HPLC)
form   powder
solubility   H2O: >5 mg/mL
originator   Merck
storage temp.   room temp

Description

Biochem/physiol Actions

Acamprosate calcium is a GABA γ-aminobutyric acid agonist.

Application

Acamprosate calcium is a GABA γ-aminobutyric acid agonist. Acamprosate calcium has been used in alcohol dependence treatments and may be an effective augmentation therapy in patients with treatment-resistant anxiety.

Features and Benefits

This compound is a featured product for Neuroscience research. Click here to discover more featured Neuroscience products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.

This compound is featured on the GABAA Receptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

This compound was developed by Merck. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

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DISCOVER Bioactive Small Molecules

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Safety & Documentation

Safety Information

Symbol 
GHS07  GHS07
Signal word 
Warning
Hazard statements 
Precautionary statements 
Personal Protective Equipment 
Hazard Codes (Europe) 
Xi
Risk Statements (Europe) 
Safety Statements (Europe) 
26-36/37/39
WGK Germany 
3

Documents

Certificate of Analysis

Protocols & Articles

Articles

Discover Bioactive Small Molecules for Neuroscience

The nervous system, comprised of the brain and spinal cord (central nervous system, or CNS) and network of nerves that connects the CNS to the rest of the body (peripheral nervous system, or PNS) is ...
Keywords: Bioactive small molecules, Central Nervous System, Diseases, Metabolism, Neurodegenerative Diseases, Neuroscience, Neurotransmission, Neurotransmitters

GABAA Receptors

GABAA receptors are responsible for the majority of neuronal inhibition in the mammalian CNS. Agonist activation results in the opening of their integral anion channel, generally leading to hyperpola...
Keywords: Anticonvulsants, Central Nervous System, Cloning, Gene expression, Ligands, Neurotransmitters, Phosphorylations, Schizophrenia, Transduction

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