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A7007 Sigma

S-(5′-Adenosyl)-L-methionine chloride dihydrochloride

≥75%

Synonym: Active methionine, AdoMet, SAM chloride dihydrochloride

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Properties

Related Categories Cancer Research, Cell Biology, Chemopreventive Agents, Coenzymes and Cofactors, Enzyme Cofactor,
InChI Key   KBAFOJZCBYWKPU-XQVUROGGSA-N
assay   ≥75%
solubility   H2O: soluble100 mg/mL
shipped in   dry ice
storage temp.   −20°C

Description

Analysis Note

Purity based on UV and HPLC.

Caution

This material is 80-90% pure when prepared, but is very unstable. As much as 10% purity loss per day at 25 °C has been noted.

Packaging

1 g in poly bottle

25, 100, 500 mg in poly bottle

5 mg in glass bottle

Biochem/physiol Actions

Methyl donor; cofactor for enzyme-catalyzed methylations, including catechol O-methyltransferase (COMT) and DNA methyltransferases (DNMT). Although present in all cells, it is concentrated in liver where 85% of all methylation reactions occur. It is also involved in regulating liver function, growth, and response to injury.

Price and Availability


All labs need water
Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
3

Documents

Certificate of Analysis

Certificate of Origin

Protocols & Articles
Peer-Reviewed Papers
15

References

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06693 Timestrip Plus -20 °C

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