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A7655 Sigma

Atenolol

≥98% (TLC), powder

Synonym: (±)-4-[2-Hydroxy-3-[(1-methylethyl)amino]propoxy]benzeneacetamide, 4-[2′-Hydroxy-3′-(isopropylamino)propoxy]phenylacetamide

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Properties

Related Categories AN-AZ, Adrenergics, Adrenergics - Antagonists, Antagonists, Approved Therapeutics/Drug Candidates,
InChI Key   METKIMKYRPQLGS-UHFFFAOYSA-N
assay   ≥98% (TLC)
form   powder
color   white to off-white
solubility   H2O: soluble0.3 mg/mL
  DMSO: soluble18 mg/mL
  ethanol: soluble3.4 mg/mL
originator   AstraZeneca
Gene Information   human ... ADRB1(153)
rat ... Adrb1(24925)

Description

Biochem/physiol Actions

Selective β1-adrenoceptor antagonist; antihypertensive; antianginal; antiarrhythmic.

Other Notes

Shelf-life of the solid is at least three years.

Application

Atenolol is a β-adrenergic blocker and used in the management of hypertension. Atenolol has antianginal and antiarrhythmic properties.

Features and Benefits

This compound is also offered as part of Sigma′s Library of Pharmacologically Active Compounds (LOPAC®1280), a biologically annotated collection of high-quality, ready-to-screen compounds. Click here to learn more.

This compound is featured on the β-Adrenoceptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

This compound was developed by AstraZeneca. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

Legal Information

LOPAC is a registered trademark of Sigma-Aldrich Co. LLC

Price and Availability


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Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
2
RTECS 
AC3600000

Documents

Certificate of Analysis

Certificate of Origin

Protocols & Articles

Articles

Antihypertensive Agents

Download BioFiles v7 n5 (3.18 Mb PDF) Back to Pharmaceutical Drugs and Drug Candidates homepage
Sami Barghshoon
BioFiles v7 n5, 2012, 5–20
Keywords: AGE, Antihypertensives, Cardiovascular, Clinical, Diuretics, Pharmaceutical, Reductions

Peer-Reviewed Papers
15

References

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Related Products

standard

Product #

Description

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06613 Atenolol-d7, analytical standard

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