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A7736 Sigma

Albumin human

recombinant, expressed in Pichia pastoris, lyophilized powder, ≥90% (agarose gel electrophoresis)

Synonym: Albagen, rHSA

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Properties

Related Categories Albumin, Biochemicals and Reagents, Human Serum Albumins, Proteins and Derivatives, Recombinant/Transgenic Human Albumins More...
recombinant   expressed in Pichia pastoris
assay   ≥90% (agarose gel electrophoresis)
form   lyophilized powder
mol wt   monomer mol wt ~67 kDa
storage temp.   2-8°C

Description

Biochem/physiol Actions

Albumins are soluble monomeric proteins found in the body fluids and tissues of animals and in some plant seeds. Serum albumin functions as a carrier protein for steroids, fatty acids, and thyroid hormones. Serum albumins are also vital in regulating the colloidal osmotic pressures of blood.

Other Notes

View more information on human serum albumin.

Packaging

1 g in poly bottle

Application

This recombinant variant is recommended for use in absorption, distribution, metabolism, and excretion (ADME) pharmacological research; cell culture; drug delivery research; and cryopreservation of cells.

Physical properties

Construct with a single deletion of Asp from the N-terminus to create a hypoallergenic construct. Structural equivalence to native albumin confirmed x-ray crystallography. The Asp deletion eliminates an important antigenic determinant by eliminating the principal copper and nickel binding site of albumin. The first three residues of human albumin are considered non-structural. Also blocked at Cys34 to improve stability, monomer content and homogeneity.

Legal Information

Albagen is a trademark of New Century Pharmaceuticals, Inc.

Price and Availability

Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
3

Documents

Certificate of Analysis

Certificate of Origin

Protocols & Articles
Peer-Reviewed Papers
15

References

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